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Ad R Hermus

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Articles 38
Citations 1076
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Recent Articles
1.
Perez-Rivas L, Simon J, Albani A, Tang S, Roeber S, Assie G, et al.
Acta Neuropathol Commun . 2022 Sep; 10(1):139. PMID: 36123588
Corticotroph macroadenomas are rare but difficult to manage intracranial neoplasms. Mutations in the two Cushing's disease mutational hotspots USP8 and USP48 are less frequent in corticotroph macroadenomas and invasive tumors....
2.
van Leeuwaarde R, Pieterman C, May A, Dekkers O, van der Horst-Schrivers A, Hermus A, et al.
Neuroendocrinology . 2020 May; 111(3):288-296. PMID: 32365349
Introduction: Multiple endocrine neoplasia type 1 (MEN1) is a hereditary endocrine tumor syndrome characterized by the triad of primary hyperparathyroidism, duodenopancreatic neuroendocrine tumors (pNETs), and pituitary tumors. Patients are confronted...
3.
Sbiera S, Perez-Rivas L, Taranets L, Weigand I, Flitsch J, Graf E, et al.
Neuro Oncol . 2019 Jun; 21(10):1273-1283. PMID: 31222332
Background: Medical treatment in Cushing's disease (CD) is limited due to poor understanding of its pathogenesis. Pathogenic variants of ubiquitin specific peptidase 8 (USP8) have been confirmed as causative in...
4.
van Leeuwaarde R, Pieterman C, Bleiker E, Dekkers O, van der Horst-Schrivers A, Hermus A, et al.
J Clin Endocrinol Metab . 2018 Apr; 103(6):2354-2361. PMID: 29618015
Objective: Multiple endocrine neoplasia type 1 (MEN1) is a hereditary disease characterized by a high risk of developing primary hyperparathyroidism, duodenopancreatic neuroendocrine tumors, and pituitary tumors (PITs). It is unclear...
5.
Perez-Rivas L, Theodoropoulou M, Puar T, Fazel J, Stieg M, Ferrau F, et al.
Eur J Endocrinol . 2017 Oct; 178(1):57-63. PMID: 28982703
Objective: Somatic mutations in the ubiquitin-specific protease 8 () gene are frequent in corticotroph tumors causing Cushing's disease (CD). Corticotroph tumor progression, the so-called Nelson's syndrome (NS), is a potentially...
6.
Conemans E, Brosens L, Raicu-Ionita G, Pieterman C, de Herder W, Dekkers O, et al.
Pancreatology . 2017 Aug; 17(5):766-772. PMID: 28811081
Background: The prognostic value of WHO grade in pancreatic neuroendocrine tumors (PanNETs) in patients with Multiple Endocrine Neoplasia Type 1 (MEN1) is unknown. Methods: We performed a cohort study using...
7.
Andela C, Repping-Wuts H, Stikkelbroeck N, Pronk M, Tiemensma J, Hermus A, et al.
Eur J Endocrinol . 2017 Jun; 177(1):59-72. PMID: 28566534
Context: Patients with pituitary disease report impairments in Quality of Life (QoL) despite optimal biomedical care. Until now, the effects of a self-management intervention (SMI) addressing psychological and social issues...
8.
Nell S, Verkooijen H, Pieterman C, de Herder W, Hermus A, Dekkers O, et al.
Ann Surg . 2017 Mar; 267(6):1155-1160. PMID: 28257328
Objective: To assess if surgery for Multiple Endocrine Neoplasia type 1 (MEN1) related nonfunctioning pancreatic neuroendocrine tumors (NF-pNETs) is effective for improving overall survival and preventing liver metastasis. Background: MEN1...
9.
Conemans E, Nell S, Pieterman C, de Herder W, Dekkers O, Hermus A, et al.
Endocr Pract . 2017 Feb; 23(6):641-648. PMID: 28225311
Objective: Duodenopancreatic neuroendocrine tumors (DP-NETs) develop in a majority of patients with multiple endocrine neoplasia type 1 (MEN1) and are the leading cause of death. Overall survival (OS) and prognostic...
10.
de Laat J, van der Luijt R, Pieterman C, Oostveen M, Hermus A, Dekkers O, et al.
BMC Med . 2016 Nov; 14(1):182. PMID: 27842554
Background: Multiple Endocrine Neoplasia type 1 (MEN1) is diagnosed when two out of the three primary MEN1-associated endocrine tumors occur in a patient. Up to 10-30 % of those patients...