Abraham M de Vos
Overview
Explore the profile of Abraham M de Vos including associated specialties, affiliations and a list of published articles.
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Articles
7
Citations
666
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0
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Recent Articles
1.
Merchant M, Vajdos F, Ultsch M, Maun H, Wendt U, Cannon J, et al.
Mol Cell Biol
. 2004 Sep;
24(19):8627-41.
PMID: 15367681
The Hedgehog pathway drives proliferation and differentiation by activating the Gli/Ci family of zinc finger transcription factors. Gli/Ci proteins form Hedgehog signaling complexes with other signaling components, including the kinesin-like...
2.
Franklin M, Carey K, Vajdos F, Leahy D, de Vos A, Sliwkowski M
Cancer Cell
. 2004 Apr;
5(4):317-28.
PMID: 15093539
We have determined the 3.2 A X-ray crystal structure of the extracellular domain of the human epidermal growth factor receptor 2 (ErbB2 or HER2) in a complex with the antigen...
3.
Christinger H, Fuh G, de Vos A, Wiesmann C
J Biol Chem
. 2003 Dec;
279(11):10382-8.
PMID: 14684734
Placental growth factor (PlGF) is a member of the vascular endothelial growth factor (VEGF) family and plays an important role in pathological angiogenic events. PlGF exerts its biological activities through...
4.
Hymowitz S, Compaan D, Yan M, Wallweber H, Dixit V, Starovasnik M, et al.
Structure
. 2003 Dec;
11(12):1513-20.
PMID: 14656435
EDA is a tumor necrosis factor family member involved in ectodermal development. Splice variants EDA-A1 and EDA-A2 differ only by the presence of Glu 308 and Val 309 in the...
5.
Vajdos F, Adams C, Breece T, Presta L, de Vos A, Sidhu S
J Mol Biol
. 2002 Jun;
320(2):415-28.
PMID: 12079396
Shotgun scanning combinatorial mutagenesis was used to study the antigen-binding site of Fab2C4, a humanized monoclonal antibody fragment that binds to the extracellular domain of the human oncogene product ErbB2....
6.
Li B, Ogasawara A, Yang R, Wei W, He G, Zioncheck T, et al.
Hypertension
. 2002 Jun;
39(6):1095-100.
PMID: 12052848
Vascular endothelial growth factor (VEGF) exerts vasodilation-induced hypotension as a major side effect for treatment of ischemic diseases. VEGF has 2 receptor tyrosine kinases, KDR and Flt-1. Little is known...
7.
Schiffer C, Ultsch M, Walsh S, Somers W, de Vos A, Kossiakoff A
J Mol Biol
. 2002 Feb;
316(2):277-89.
PMID: 11851338
The structure of the ternary complex between the phage display- optimized, high-affinity Site 1 variant of human growth hormone (hGH) and two copies of the extracellular domain (ECD) of the...