Abiola O Olaitan
Overview
Explore the profile of Abiola O Olaitan including associated specialties, affiliations and a list of published articles.
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8
Citations
731
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Recent Articles
1.
Olaitan A, Dureja C, Youngblom M, Topf M, Shen W, Gonzales-Luna A, et al.
Nat Commun
. 2023 Jul;
14(1):4130.
PMID: 37438331
Severe outbreaks and deaths have been linked to the emergence and global spread of fluoroquinolone-resistant Clostridioides difficile over the past two decades. At the same time, metronidazole, a nitro-containing antibiotic,...
2.
Dureja C, Olaitan A, Hurdle J
Curr Opin Microbiol
. 2022 Jan;
66:63-72.
PMID: 35077947
The evolution of antimicrobial resistance in Clostridioides difficile has markedly shaped its epidemiology and detrimentally impacted patient care. C. difficile exhibits resistance to multiple classes of antimicrobials, due to accumulation...
3.
Marreddy R, Olaitan A, May J, Dong M, Hurdle J
Microbiol Spectr
. 2021 Sep;
9(2):e0044821.
PMID: 34468187
Ebselen, a reactive organoselenium compound, was shown to inhibit toxins TcdA and TcdB by covalently binding to their cysteine protease domains. It was suggested that ebselen lacked antimicrobial activity against...
4.
Gonzales-Luna A, Olaitan A, Shen W, Deshpande A, Carlson T, Dotson K, et al.
Open Forum Infect Dis
. 2021 Aug;
8(8):ofab365.
PMID: 34381844
Background: Clinical studies have demonstrated inferior cure rates when metronidazole (MTZ) is used to treat infection (CDI). We hypothesized that a newly identified, heme-inducible form of reduced MTZ susceptibility in...
5.
Wu X, Shen W, Deshpande A, Olaitan A, Palmer K, Garey K, et al.
J Clin Microbiol
. 2021 Jun;
59(9):e0058521.
PMID: 34132582
Metronidazole resistance in clinical Clostridioides difficile is often described as unstable, since resistant strains reportedly appear susceptible following freezer storage or brief passage. This has presented a conundrum for adopting...
6.
Olaitan A, Aballay A
PLoS Genet
. 2018 Sep;
14(9):e1007693.
PMID: 30265660
GATA transcription factors play a crucial role in the regulation of immune functions across metazoans. In Caenorhabditis elegans, the GATA transcription factor ELT-2 is involved in the control of not...
7.
Head B, Olaitan A, Aballay A
Virulence
. 2016 Sep;
8(3):261-274.
PMID: 27600703
Infectious diseases caused by bacterial pathogens reduce the fitness of their associated host but are generally limited in duration. In order for the diseased host to regain any lost fitness...
8.
Olaitan A, Morand S, Rolain J
Front Microbiol
. 2014 Dec;
5:643.
PMID: 25505462
Polymyxins are polycationic antimicrobial peptides that are currently the last-resort antibiotics for the treatment of multidrug-resistant, Gram-negative bacterial infections. The reintroduction of polymyxins for antimicrobial therapy has been followed by...