Abigail Fosdick
Overview
Explore the profile of Abigail Fosdick including associated specialties, affiliations and a list of published articles.
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4
Citations
317
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0
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Recent Articles
1.
Menne S, Tumas D, Liu K, Thampi L, Aldeghaither D, Baldwin B, et al.
J Hepatol
. 2015 Jan;
62(6):1237-45.
PMID: 25559326
Background & Aims: New therapies for chronic hepatitis B (CHB) are urgently needed since current treatments rarely lead to cure. We evaluated whether the oral small molecule toll-like receptor (TLR7)...
2.
Fosdick A, Zheng J, Pflanz S, Frey C, Hesselgesser J, Halcomb R, et al.
J Pharmacol Exp Ther
. 2013 Oct;
348(1):96-105.
PMID: 24133297
GS-9620 [8-(3-(pyrrolidin-1-ylmethyl)benzyl)-4-amino-2-butoxy-7,8-dihydropteridin-6(5H)-one] is a potent, orally bioavailable small-molecule agonist of Toll-like receptor 7 (TLR7) developed for finite treatment of chronic hepatitis B viral (HBV) infection, with the goal of inducing...
3.
Lanford R, Guerra B, Chavez D, Giavedoni L, Hodara V, Brasky K, et al.
Gastroenterology
. 2013 Feb;
144(7):1508-17, 1517.e1-10.
PMID: 23415804
Background & Aims: Direct-acting antiviral agents suppress hepatitis B virus (HBV) load, but they require life-long use. Stimulation of the innate immune system could increase its ability to control the...
4.
Chui R, Fosdick A, Conner R, Jiang J, Bruenner B, Vargas H
J Pharmacol Toxicol Methods
. 2009 May;
60(1):58-68.
PMID: 19426820
Introduction: Regulatory guidelines recommend the use of conscious, unrestrained animals for comprehensive cardiovascular safety assessment of a new therapeutic agent. Cardiovascular safety pharmacology studies normally use internal telemetry (surgical implants)...