Abha K Rajbhandari
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Explore the profile of Abha K Rajbhandari including associated specialties, affiliations and a list of published articles.
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19
Citations
466
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Recent Articles
1.
Shetty S, Duesman S, Patel S, Huynh P, Toh P, Shroff S, et al.
Biol Sex Differ
. 2024 Jul;
15(1):55.
PMID: 39010139
Background: Scientific evidence highlights the influence of biological sex on the relationship between stress and metabolic dysfunctions. However, there is limited understanding of how diet and stress concurrently contribute to...
2.
Shetty S, Duesman S, Patel S, Huyhn P, Shroff S, Das A, et al.
bioRxiv
. 2023 Nov;
PMID: 38014350
Scientific evidence underscores the influence of biological sex on the interplay between stress and metabolic dysfunctions. However, there is limited understanding of how diet and stress jointly contribute to metabolic...
3.
Patel S, Sparman N, Arneson D, Alvarsson A, Santos L, Duesman S, et al.
Nature
. 2023 Jul;
620(7972):192-199.
PMID: 37495690
Sympathetic activation during cold exposure increases adipocyte thermogenesis via the expression of mitochondrial protein uncoupling protein 1 (UCP1). The propensity of adipocytes to express UCP1 is under a critical influence...
4.
Rajbhandari A, Barson J, Gilmartin M, Hammack S, Chen B
Neurobiol Learn Mem
. 2023 Jun;
203:107792.
PMID: 37369343
Pituitary adenylate cyclase-activating peptide (PACAP) is a highly conserved and widely expressed neuropeptide that has emerged as a key regulator of multiple neural and behavioral processes. PACAP systems, including the...
5.
Ago Y, Van C, Condro M, Hrncir H, Diep A, Rajbhandari A, et al.
Exp Neurol
. 2023 Jan;
362:114339.
PMID: 36717013
Large scale studies in populations of European and Han Chinese ancestry found a series of rare gain-of-function microduplications in VIPR2, encoding VPAC2, a receptor that binds vasoactive intestinal peptide and...
6.
Nishimura K, Poulos A, Drew M, Rajbhandari A
Neurosci Biobehav Rev
. 2022 Sep;
142:104884.
PMID: 36174795
Extreme stress can cause long-lasting changes in affective behavior manifesting in conditions such as post-traumatic stress disorder (PTSD). Understanding the biological mechanisms that govern trauma-induced behavioral dysregulation requires reliable and...
7.
Rajbhandari A, Octeau C, Gonzalez S, Pennington Z, Mohamed F, Trott J, et al.
J Neurosci
. 2021 Feb;
41(15):3446-3461.
PMID: 33637560
Trauma can cause dysfunctional fear regulation leading some people to develop disorders, such as post-traumatic stress disorder (PTSD). The amygdala regulates fear, whereas PACAP (pituitary adenylate activating peptide) and PAC1...
8.
Pennington Z, Trott J, Rajbhandari A, Li K, Walwyn W, Evans C, et al.
Neuropsychopharmacology
. 2019 Dec;
45(3):482-490.
PMID: 31787748
Despite the large comorbidity between PTSD and opioid use disorders, as well as the common treatment of physical injuries resulting from trauma with opioids, the ability of opioid treatments to...
9.
Rajbhandari P, Arneson D, Hart S, Ahn I, Diamante G, Santos L, et al.
Elife
. 2019 Oct;
8.
PMID: 31644425
Immune cells are vital constituents of the adipose microenvironment that influence both local and systemic lipid metabolism. Mice lacking IL10 have enhanced thermogenesis, but the roles of specific cell types...
10.
Nagai J, Rajbhandari A, Gangwani M, Hachisuka A, Coppola G, Masmanidis S, et al.
Cell
. 2019 Apr;
177(5):1280-1292.e20.
PMID: 31031006
Hyperactivity and disturbances of attention are common behavioral disorders whose underlying cellular and neural circuit causes are not understood. We report the discovery that striatal astrocytes drive such phenotypes through...