Abdul Rauf Siddiqi
Overview
Explore the profile of Abdul Rauf Siddiqi including associated specialties, affiliations and a list of published articles.
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Articles
24
Citations
183
Followers
0
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Recent Articles
1.
Saddiqa A, Zakir M, Sheikh M, Muneer Z, Hassan A, Ali I, et al.
Sci Rep
. 2024 Oct;
14(1):24049.
PMID: 39402118
No abstract available.
2.
Saddiqa A, Zakir M, Sheikh M, Muneer Z, Hassan A, Ali I, et al.
Sci Rep
. 2024 Sep;
14(1):20840.
PMID: 39242688
Breast cancer (BC) is a malignant neoplasm which is classified into various types defined by underlying molecular factors such as estrogen receptor positive (ER+), progesterone receptor positive (PR+), human epidermal...
3.
Ali I, Iqbal M, Ibrahim M, Ul Haq I, Alonazi W, Siddiqi A
PLoS One
. 2023 Nov;
18(11):e0294511.
PMID: 37972144
Cardiovascular disorders are the world's major cause of death nowadays. To treat cardiovascular diseases especially coronary artery diseases and hypertension, researchers found potential ROCK2 (Rho-associated coiled-coil-containing protein kinase 2) target...
4.
Tahir A, Siddiqi A, Maryam A, Vedithi S, Blundell T
J Biomol Struct Dyn
. 2023 Oct;
42(21):11717-11730.
PMID: 37814544
is a species of moth in the Crambidae family that is harmful to maize and other corn crops in Southeast Asia and the Western Pacific regions. causes devastating losses to...
5.
Maryam A, Siddiqi A, Vedithi S, Ece A, Khalid R
J Biomol Struct Dyn
. 2023 Aug;
42(15):7812-7827.
PMID: 37545162
The inhibition of Phosphodiesterase 5A (PDEA5) has the potential to modulate pulmonary arterial hypertension and cardiovascular diseases. Exploring the cross-reactivity of clinically available PDE5A therapeutics with PDE6A is intriguing in...
6.
Khalid R, Maryam A, Cinaroglu S, Siddiqi A, Sezerman O
J Biomol Struct Dyn
. 2021 Feb;
40(13):6128-6150.
PMID: 33522438
Modulating the activity of human soluble guanylate cyclase (sGC) through allosteric regulation of the βH-NOX domain has been considered as an immediate treatment for cardiovascular disorder (CVDs). Currently available βH-NOX...
7.
Sadiq S, Rana N, Zahid M, Zargaham M, Tanweer T, Batool A, et al.
Molecules
. 2020 Aug;
25(16).
PMID: 32824118
is a Gram-negative pathogenic bacterium that is present commonly in soil and water and is responsible for causing septic shock, pneumonia, urinary tract and gastrointestinal infections, etc. The multi-drug resistance...
8.
Maryam A, Khalid R, Vedithi S, Ece A, Cinaroglu S, Siddiqi A, et al.
Comput Struct Biotechnol J
. 2020 Jul;
18:1625-1638.
PMID: 32670503
Protein kinase Iα (PKGIα) is a pivotal cyclic guanosine monophosphate (cGMP) signalling protein. Major steps related to the structural plasticity of PKGIα have been inferred but the structural aspects of...
9.
Khalid R, Maryam A, Sezerman O, Mylonas E, Siddiqi A, Kokkinidis M
Sci Rep
. 2020 Jun;
10(1):9488.
PMID: 32528025
In the nitric oxide (NO) signaling pathway, human soluble guanylate cyclase (hsGC) synthesizes cyclic guanosine monophosphate (cGMP); responsible for the regulation of cGMP-specific protein kinases (PKGs) and phosphodiesterases (PDEs). The...
10.
Maryam A, Khalid R, Siddiqi A, Ece A
J Biomol Struct Dyn
. 2020 Apr;
39(7):2302-2317.
PMID: 32299297
The need of circumventing life-threatening cardiovascular disorders (CVDs) and pulmonary hypertension (PHT) worldwide prompts researchers to develop effective therapeutic agents. Crucial role of cyclic nucleotide phosphodiesterase-5 (PDE5A) and cyclic nucleotide...