Abdellah Belmaaza
Overview
Explore the profile of Abdellah Belmaaza including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
7
Citations
273
Followers
0
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Recent Articles
1.
Cousineau I, Belmaaza A
Mol Genet Genomics
. 2011 Mar;
285(4):325-40.
PMID: 21409565
EMSY links the BRCA2 pathway to sporadic breast/ovarian cancer. It encodes a nuclear protein that binds to the BRCA2 N-terminal domain implicated in chromatin/transcription regulation, but when sporadically amplified/overexpressed, increased...
2.
Chan N, Koritzinsky M, Zhao H, Bindra R, Glazer P, Powell S, et al.
Cancer Res
. 2008 Jan;
68(2):605-14.
PMID: 18199558
Hypoxic and/or anoxic tumor cells can have increased rates of mutagenesis and altered DNA repair protein expression. Yet very little is known regarding the functional consequences of any hypoxia-induced changes...
3.
Cousineau I, Belmaaza A
Cell Cycle
. 2007 Apr;
6(8):962-71.
PMID: 17404506
Humans heterozygous for BRCA1 mutations have a high risk of losing the remaining wild-type BRCA1 allele and developing breast/ovarian cancer, but a molecular basis for this has not yet been...
4.
Cousineau I, Abaji C, Belmaaza A
Cancer Res
. 2005 Dec;
65(24):11384-91.
PMID: 16357146
The breast/ovarian cancer susceptibility proteins BRCA1 and BRCA2 maintain genome stability, at least in part, through a functional role in DNA damage repair. They both colocalize with RAD51 at sites...
5.
Lemelin J, Abaji C, Cousineau I, Belmaaza A
Cell Cycle
. 2005 May;
4(6):831-7.
PMID: 15908792
In addition to its well established role in the maintenance of genome integrity by regulating transcription of genes involved in cell cycle arrest and programmed cell death, the tumour suppressor...
6.
Abaji C, Cousineau I, Belmaaza A
Cancer Res
. 2005 May;
65(10):4117-25.
PMID: 15899802
BRCA2 has been implicated in the maintenance of genome stability and RAD51-mediated homologous recombination repair of chromosomal double-strand breaks (DSBs), but its role in these processes is unclear. To gain...
7.
Villemure J, Abaji C, Cousineau I, Belmaaza A
Cancer Res
. 2003 Jun;
63(12):3334-9.
PMID: 12810667
Mutations in the mismatch repair (MMR) genes hMSH2 and hMLH1 have been associated with hereditary nonpolyposis colorectal cancer. Tumor cell lines that are deficient in MMR exhibit a high mutation...