Abdelilah Wakkach
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Explore the profile of Abdelilah Wakkach including associated specialties, affiliations and a list of published articles.
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26
Citations
1263
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Recent Articles
1.
Munoz-Garcia J, Vargas-Franco J, Schiavone K, Keatinge M, Young R, Amiaud J, et al.
Theranostics
. 2025 Mar;
15(7):3185-3202.
PMID: 40083929
During development, the contribution of IL34, a ligand of macrophage colony stimulating factor receptor (MCSFR), has not been fully defined. Together with its twin cytokine MCSF, they display an essential...
2.
Madel M, Ibanez L, Ciucci T, Halper J, Boutin A, Beldi G, et al.
Mucosal Immunol
. 2024 Sep;
18(1):90-104.
PMID: 39332768
Inflammatory bowel disease (IBD) is characterized by very severe intestinal inflammation associated with extra-intestinal manifestations. One of the most critical ones is bone destruction, which remains a major cause of...
3.
Madel M, Halper J, Ibanez L, Claire L, Rouleau M, Boutin A, et al.
Elife
. 2023 Feb;
12.
PMID: 36848406
Bone destruction is a hallmark of chronic inflammation, and bone-resorbing osteoclasts arising under such a condition differ from steady-state ones. However, osteoclast diversity remains poorly explored. Here, we combined transcriptomic...
4.
Dolfi B, Gallerand A, Firulyova M, Xu Y, Merlin J, Dumont A, et al.
Cell Rep
. 2022 Jun;
39(11):110949.
PMID: 35705045
Despite the ubiquitous function of macrophages across the body, the diversity, origin, and function of adrenal gland macrophages remain largely unknown. We define the heterogeneity of adrenal gland immune cells...
5.
Madel M, Ibanez L, Ciucci T, Halper J, Rouleau M, Boutin A, et al.
Elife
. 2020 May;
9.
PMID: 32400390
Bone destruction relies on interactions between bone and immune cells. Bone-resorbing osteoclasts (OCLs) were recently identified as innate immune cells activating T cells toward tolerance or inflammation. Thus, pathological bone...
6.
Madel M, Ibanez L, Wakkach A, de Vries T, Teti A, Apparailly F, et al.
Front Immunol
. 2019 Jul;
10:1408.
PMID: 31275328
Osteoclasts (OCLs) are key players in controlling bone remodeling. Modifications in their differentiation or bone resorbing activity are associated with a number of pathologies ranging from osteopetrosis to osteoporosis, chronic...
7.
Madel M, Ibanez L, Rouleau M, Wakkach A, Blin-Wakkach C
Front Immunol
. 2018 Nov;
9:2567.
PMID: 30450105
Osteoclasts (OCLs) are multinucleated phagocytes of monocytic origin responsible for physiological and pathological bone resorption including aging processes, chronic inflammation and cancer. Besides bone resorption, they are also involved in...
8.
Ibanez L, Rouleau M, Wakkach A, Blin-Wakkach C
Joint Bone Spine
. 2018 Apr;
86(1):43-47.
PMID: 29654948
The gut microbiome is now viewed as a tissue that interacts bidirectionally with the gastrointestinal, immune, endocrine and nervous systems, affecting the cellular responses in numerous organs. Evidence is accumulating...
9.
Roux C, Saviane G, Pini J, Belaid N, Dhib G, Voha C, et al.
Front Immunol
. 2018 Feb;
8:1991.
PMID: 29422893
Despite mesenchymal stromal cells (MSCs) are considered as a promising source of cells to modulate immune functions on cells from innate and adaptive immune systems, their clinical use remains restricted...
10.
Zeboudj L, Maitre M, Guyonnet L, Laurans L, Joffre J, Lemarie J, et al.
J Am Coll Cardiol
. 2018 Jan;
71(2):160-172.
PMID: 29325640
Background: Several epidermal growth factor receptor (EGFR) inhibitors have been successfully developed for the treatment of cancer, limiting tumor growth and metastasis. EGFR is also expressed by leukocytes, but little...