Aaron R Ellison
Overview
Explore the profile of Aaron R Ellison including associated specialties, affiliations and a list of published articles.
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13
Citations
473
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Recent Articles
1.
Serrano A, Rocha P, Lima C, Stewart A, Zhang B, Diao L, et al.
NPJ Precis Oncol
. 2024 Nov;
8(1):268.
PMID: 39558076
Delta-like Ligand 3 (DLL3) targeting therapies are promising in small cell lung cancer (SCLC) treatment. However, DLL3 expression in SCLC and other neuroendocrine neoplasms (NEN) is heterogeneous and not well...
2.
Zhan J, Felder B, Ellison A, Winters A, Salimi-Moosavi H, Scully S, et al.
Monoclon Antib Immunodiagn Immunother
. 2013 Jun;
32(3):149-61.
PMID: 23750472
Thrombopoietin and its cognate receptor, c-Mpl, are the primary molecular regulators of megakaryocytopoiesis and platelet production. To date the pattern of c-Mpl expression in human solid tumors and the distribution...
3.
Babij C, Zhang Y, Kurzeja R, Munzli A, Shehabeldin A, Fernando M, et al.
Cancer Res
. 2011 Jul;
71(17):5818-26.
PMID: 21742770
Despite the prevalence of KRAS mutations in human cancers, there remain no targeted therapies for treatment. The serine-threonine kinase STK33 has been proposed to be required for the survival of...
4.
Mouse monoclonal antibodies against human c-Mpl and characterization for flow cytometry applications
Abbott C, Huang G, Ellison A, Chen C, Arora T, Szilvassy S, et al.
Hybridoma (Larchmt)
. 2010 May;
29(2):103-13.
PMID: 20443702
Mouse monoclonal antibodies (MAbs) against human c-Mpl, the cognate receptor for thrombopoietin (TPO), were generated using hybridoma technology and characterized by various assays to demonstrate their specificity and affinity. Two...
5.
Swift S, Ellison A, Kassner P, McCaffery I, Rossi J, Sinclair A, et al.
Blood
. 2010 Feb;
115(21):4254-63.
PMID: 20124514
Certain oncology trials showed worse clinical outcomes in the erythropoiesis-stimulating agent (ESA) arm. A potential explanation was that ESA-activated erythropoietin (Epo) receptors (EpoRs) promoted tumor cell growth. Although there were...
6.
Sasu B, Cooke K, Arvedson T, Plewa C, Ellison A, Sheng J, et al.
Blood
. 2010 Jan;
115(17):3616-24.
PMID: 20053755
Iron maldistribution has been implicated in multiple diseases, including the anemia of inflammation (AI), atherosclerosis, diabetes, and neurodegenerative disorders. Iron metabolism is controlled by hepcidin, a 25-amino acid peptide. Hepcidin...
7.
Arora T, Padaki R, Liu L, Hamburger A, Ellison A, Stevens S, et al.
Cytokine
. 2009 Jan;
45(2):124-31.
PMID: 19128982
There are currently two Food and Drug Administration-approved classes of biologic agents that target tumor necrosis factor-alpha (TNF-alpha): anti-TNF monoclonal antibodies (mAbs) (adalimumab and infliximab), and soluble TNF receptors (etanercept)....
8.
Ellison A, Lofing J, Bitter G
Nucleic Acids Res
. 2004 Oct;
32(18):5321-38.
PMID: 15475387
Germline mutations in the DNA mismatch repair (MMR) genes MSH2 and MLH1 are responsible for the majority of hereditary non-polyposis colorectal cancer (HNPCC), an autosomal-dominant early-onset cancer syndrome. Genetic testing...
9.
van Tuyl M, Blommaart P, de Boer P, Wert S, Ruijter J, Islam S, et al.
Dev Biol
. 2004 Jul;
272(1):104-17.
PMID: 15242794
Maternal hypothyroxinemia during early pregnancy poses an increased risk for poor neuropsychological development of the fetus. We tested the hypothesis that maternal hypothyroidism before the onset of fetal thyroid function...
10.
Ellison A, Lofing J, Bitter G
J Steroid Biochem Mol Biol
. 2003 Aug;
86(1):15-26.
PMID: 12943741
The yeast Saccharomyces cerevisiae was used to reconstruct a human estrogen receptor alpha (ERalpha)-mediated transcription activation system. The level of reporter gene activation was dependent on both the position of...