Aaron H Wasserman
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Explore the profile of Aaron H Wasserman including associated specialties, affiliations and a list of published articles.
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9
Citations
350
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Recent Articles
1.
Neitzel L, Silver M, Wasserman A, Rea S, Hong C, Williams C
Dev Dyn
. 2025 Jan;
PMID: 39840753
Disruption of extracellular pH and proton-sensing can profoundly impact cellular and protein functions, leading to developmental defects. To visualize changes in extracellular pH in the developing embryo, we generated a...
2.
Kostina A, Lewis-Israeli Y, Abdelhamid M, Gabalski M, Kiselev A, Volmert B, et al.
Stem Cell Reports
. 2024 Feb;
19(3):317-330.
PMID: 38335962
Congenital heart defects are the most prevalent human birth defects, and their incidence is exacerbated by maternal health conditions, such as diabetes during the first trimester (pregestational diabetes). Our understanding...
3.
Kostina A, Lewis-Israeli Y, Abdelhamid M, Gabalski M, Volmert B, Lankerd H, et al.
bioRxiv
. 2023 Jun;
PMID: 37333095
Congenital heart defects constitute the most common birth defect in humans, affecting approximately 1% of all live births. The incidence of congenital heart defects is exacerbated by maternal conditions, such...
4.
Wasserman A, Huang A, Lewis-Israeli Y, Dooley M, Mitchell A, Venkatesan M, et al.
Front Cell Dev Biol
. 2022 Oct;
10:985298.
PMID: 36247002
Cardiovascular disease (CVD) is one of the leading causes of mortality worldwide, and frequently leads to massive heart injury and the loss of billions of cardiac muscle cells and associated...
5.
Lewis-Israeli Y, Wasserman A, Aguirre A
Biomolecules
. 2021 Sep;
11(9).
PMID: 34572490
Organoids are three-dimensional in vitro cell constructs that recapitulate organ properties and structure to a significant extent. They constitute particularly useful models to study unapproachable states in humans, such as...
6.
Lewis-Israeli Y, Wasserman A, Gabalski M, Volmert B, Ming Y, Ball K, et al.
Nat Commun
. 2021 Aug;
12(1):5142.
PMID: 34446706
Congenital heart defects constitute the most common human birth defect, however understanding of how these disorders originate is limited by our ability to model the human heart accurately in vitro....
7.
Wasserman A, Venkatesan M, Aguirre A
Cells
. 2020 Jun;
9(6).
PMID: 32503253
Cardiovascular disease (CVD) remains a leading cause of death globally. Understanding and characterizing the biochemical context of the cardiovascular system in health and disease is a necessary preliminary step for...
8.
Helms A, Tang V, OLeary T, Friedline S, Wauchope M, Arora A, et al.
JCI Insight
. 2019 Dec;
5(2).
PMID: 31877118
Mutations in cardiac myosin binding protein C (MyBP-C, encoded by MYBPC3) are the most common cause of hypertrophic cardiomyopathy (HCM). Most MYBPC3 mutations result in premature termination codons (PTCs) that...
9.
Chopra R, Wasserman A, Pulst S, De Zeeuw C, Shakkottai V
Hum Mol Genet
. 2018 Feb;
27(8):1396-1410.
PMID: 29432535
Among the many types of neurons expressing protein kinase C (PKC) enzymes, cerebellar Purkinje neurons are particularly reliant on appropriate PKC activity for maintaining homeostasis. The importance of PKC enzymes...
10.
DellOrco J, Wasserman A, Chopra R, Ingram M, Hu Y, Singh V, et al.
J Neurosci
. 2015 Aug;
35(32):11292-307.
PMID: 26269637
Significance Statement: In neurodegenerative disease, neuronal atrophy has long been assumed to be an early nonspecific event preceding neuronal loss. However, in a mouse model of spinocerebellar ataxia type 1...