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Aaron Barksdale

Explore the profile of Aaron Barksdale including associated specialties, affiliations and a list of published articles. Areas
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Recent Articles
1.
Schaich C, Chappell M, Shotwell M, Joly M, Gibbs K, Barksdale A, et al.
Am J Physiol Lung Cell Mol Physiol . 2025 Jan; 328(3):L405-L412. PMID: 39884670
SARS-CoV-2 targets angiotensin-converting enzyme-2 (ACE2), a key peptidase of the renin-angiotensin system (RAS), which regulates the balance of the vasoconstrictor/inflammatory peptide Ang II and the vasodilator/anti-inflammatory peptide Ang-(1-7). Few studies...
2.
Collins S, Shotwell M, Strich J, Gibbs K, de Wit M, Files D, et al.
JAMA Netw Open . 2024 Dec; 7(12):e2448215. PMID: 39625722
Importance: Fostamatinib, a spleen tyrosine kinase inhibitor, has been reported to improve outcomes of COVID-19. Objective: To evaluate the efficacy and safety of fostamatinib in adults hospitalized with COVID-19 and...
3.
Self W, Shotwell M, Gibbs K, de Wit M, Files D, Harkins M, et al.
JAMA . 2023 Apr; 329(14):1170-1182. PMID: 37039791
Importance: Preclinical models suggest dysregulation of the renin-angiotensin system (RAS) caused by SARS-CoV-2 infection may increase the relative activity of angiotensin II compared with angiotensin (1-7) and may be an...
4.
Barksdale A, Hackman J, Bonham A, Gratton M
Am J Emerg Med . 2014 Aug; 32(10):1208-11. PMID: 25124026
Background: We initiated a program to rapidly rule out myocardial infarction and make an appointment (with no co-payment) with a cardiologist within 72 hours for patients with low-risk chest pain....