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A W Rowbottom

Explore the profile of A W Rowbottom including associated specialties, affiliations and a list of published articles. Areas
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Articles 18
Citations 179
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Recent Articles
1.
Saleem R, Keymer C, Patel D, Egner W, Rowbottom A
Clin Exp Immunol . 2017 Apr; 188(3):387-393. PMID: 28423454
The clinical utility of molecular diagnostic approaches in allergy investigation is being recognized increasingly to play a significant role in the management of allergic patients. Determining the sensitization pattern, which...
2.
Shah D, Rowbottom A, Thomas C, Cumber P, Chowdhury M
Br J Dermatol . 2007 Jun; 157(2):392-3. PMID: 17553046
No abstract available.
3.
Sudheer P, Hall J, Read G, Rowbottom A, Williams P
Anaesthesia . 2005 Feb; 60(3):251-6. PMID: 15710010
The investigation of anaphylactic reactions in the peri-operative period is difficult. Elevation of serum tryptase levels is a good indicator of an anaphylactic event but the ability of subsequent investigations...
4.
Al-Shanti N, Steward C, Garland R, Rowbottom A
Immunology . 2004 Jun; 112(3):397-403. PMID: 15196207
In order to determine molecules involved in the differentiation and proliferation of human CD8(+) cells, two ex vivo expansion models were established: coculture of freshly purified human CD8(+) cells with...
5.
Garland R, West S, Hancock J, Goulden N, Steward C, Rowbottom A
Scand J Immunol . 2002 Feb; 55(1):61-9. PMID: 11841693
Cytotoxic T lymphocytes (CTL) are important for the recognition and lysis of virally infected cells, but their effectiveness can be limited by viral immune evasion mechanisms. We investigated the immunophenotype...
6.
Blair A, Rowbottom A, Browne S, Goulden N, Steward C, Oakhill A, et al.
Leukemia . 2001 Oct; 15(10):1596-603. PMID: 11587218
We have tested the hypothesis that functional dendritic cells (DC) may be generated from patients with acute lymphoblastic leukaemia (ALL). We evaluated the production of DC from blast cells taken...
7.
Rowbottom A, Garland R, Lepper M, Kaneria S, Goulden N, Oakhill A, et al.
Br J Haematol . 2000 Sep; 110(2):315-21. PMID: 10971387
The biological activities of CD8+ that co-express CD57 remain poorly defined. It is unclear whether all CD8+ cells have the potential to become CD57+ or whether they represent a unique...
8.
Garland R, Kaneria S, Hancock J, Steward C, Rowbottom A
J Immunol Methods . 1999 Sep; 227(1-2):53-63. PMID: 10485254
We have investigated the ability of Teflon cell culture (TCC) bags, compared to conventional tissue culture flasks and plates, to support the expansion of human CD8+ T cells in response...
9.
Rowbottom A, Lepper M, Garland R, Cox C, Corley E
Immunology . 1999 Sep; 98(1):80-9. PMID: 10469237
Interleukin (IL)-10, a product of T helper 2 (Th2) lymphocytes, has been shown to be an important regulator of lymphoid and myeloid cells, inhibiting mitogen, peptide and alloantigen-induced T-cell proliferation...
10.
Knechtli C, Goulden N, Hancock J, Grandage V, Harris E, Garland R, et al.
Blood . 1998 Dec; 92(11):4072-9. PMID: 9834212
The efficacy of allografting in acute lymphoblastic leukemia (ALL) is heavily influenced by remission status at the time of transplant. Using polymerase chain reaction (PCR)-based minimal residual disease (MRD) analysis,...