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A W Purcell

Explore the profile of A W Purcell including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 359
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Recent Articles
1.
Faridi P, Dorvash M, Purcell A
Clin Exp Immunol . 2021 Mar; 204(2):179-188. PMID: 33644851
Peptides that bind to and are presented on the cell surface by human leucocyte antigen (HLA) molecules play a critical role in adaptive immunity. For a long time it was...
2.
Giam K, Ayala-Perez R, Illing P, Schittenhelm R, Croft N, Purcell A, et al.
Tissue Antigens . 2015 Apr; 85(6):492-6. PMID: 25880248
Human leukocyte antigen (HLA)-A1 is one of the most common Caucasian HLA-A alleles. Here, we describe the comprehensive analysis of the HLA-A*01:01 ligand repertoire with the identification of 4735 naturally...
3.
Gresle M, Liu Y, Dagley L, Haartsen J, Pearson F, Purcell A, et al.
J Neurol Neurosurg Psychiatry . 2014 Mar; 85(11):1209-13. PMID: 24639436
Objectives: We evaluated whether the measurement of serum phosphorylated neurofilament heavy chain (pNF-H) titre is likely to be a valid biomarker of axonal injury in multiple sclerosis (MS). Methods: Serum...
4.
Schittenhelm R, Dudek N, Croft N, Ramarathinam S, Purcell A
Tissue Antigens . 2014 Jan; 83(3):174-9. PMID: 24397554
The human B lymphoblastoid cell line C1R is widely regarded as human leukocyte antigen-A (HLA-A)/HLA-B negative and is therefore frequently exploited as a recipient cell line to study HLA class...
5.
Mannering S, Pang S, Williamson N, Naselli G, Reynolds E, OBrien-Simpson N, et al.
Clin Exp Immunol . 2009 Mar; 156(2):226-31. PMID: 19292763
Type 1 diabetes (T1D) is caused by T cell-mediated destruction of the pancreatic insulin-producing beta cells. While the role of CD4(+) T cells in the pathogenesis of T1D is accepted...
6.
Mifsud N, Purcell A, Chen W, Holdsworth R, Tait B, McCluskey J
Am J Transplant . 2007 Dec; 8(1):121-32. PMID: 18093278
Allogeneic solid organ transplantation often occurs across multiple donor-recipient HLA mismatches with consequent risk of allograft rejection. However, there is growing evidence that not all HLA mismatches are equivalent in...
7.
Steuten J, Winkel K, Carroll T, Williamson N, Ignjatovic V, Fung K, et al.
Toxicon . 2007 Oct; 50(8):1041-52. PMID: 17904179
The Snake Venom Detection Kit (SVDK) is of major medical importance in Australia, yet it has never been rigorously characterised in terms of its sensitivity and specificity, especially when it...
8.
Purcell A, Gorman J
Mol Cell Proteomics . 2004 Jan; 3(3):193-208. PMID: 14718575
The mammalian immune system has evolved to display fragments of protein antigens derived from microbial pathogens to immune effector cells. These fragments are typically peptides liberated from the intact antigens...
9.
Chang L, Kjer-Nielsen L, Flynn S, Brooks A, Mannering S, Honeyman M, et al.
Tissue Antigens . 2003 Nov; 62(5):408-17. PMID: 14617048
We describe a strategy for identifying ligands of human leukocyte antigen (HLA) class I molecules based on a peptide library-mediated in vitro assembly of recombinant class I molecules. We established...
10.
Purcell A, Todd A, Kinoshita G, Lynch T, Keech C, Gething M, et al.
Clin Exp Immunol . 2003 Apr; 132(2):193-200. PMID: 12699405
Patterns of autoantibody production are diagnostic of many autoimmune disorders; the recent observation of additional autospecificities towards stress-induced proteins may also provide insight into the mechanisms by which such responses...