A van der Gaast
Overview
Explore the profile of A van der Gaast including associated specialties, affiliations and a list of published articles.
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77
Citations
3101
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Recent Articles
1.
de Jongh M, Eyck B, van der Werf L, Toxopeus E, van Lanschot J, Lagarde S, et al.
BJS Open
. 2021 Apr;
5(2).
PMID: 33876211
Background: Neoadjuvant chemoradiotherapy (nCRT) and surgery is a widely used treatment for locally advanced resectable oesophageal cancer, with 20-50 per cent of patients having a pathological complete response (pCR). Disease,...
2.
Noordman B, Verdam M, Onstenk B, Heisterkamp J, Jansen W, Martijnse I, et al.
Ann Surg Oncol
. 2019 Oct;
26(13):4765-4772.
PMID: 31620943
Background: The course of health-related quality of life (HRQOL) during and after completion of neoadjuvant chemoradiotherapy (nCRT) for esophageal or junctional carcinoma is unknown. Methods: This study was a multicenter...
3.
Eyck B, van der Wilk B, Lagarde S, Wijnhoven B, Valkema R, Spaander M, et al.
Best Pract Res Clin Gastroenterol
. 2018 Dec;
36-37:37-44.
PMID: 30551855
At present, treatment of potentially curable oesophageal cancer includes neoadjuvant chemoradiotherapy followed by oesophagectomy. Alternatively, neoadjuvant chemotherapy is used. To date, strong evidence on the superiority of one modality over...
4.
Noordman B, Verdam M, Lagarde S, Shapiro J, Hulshof M, van Berge Henegouwen M, et al.
Ann Oncol
. 2017 Nov;
29(2):445-451.
PMID: 29126244
Background: Neoadjuvant chemoradiotherapy (nCRT) plus surgery is a standard of care for patients with esophageal or junctional cancer, but the long-term impact of nCRT on health-related quality of life (HRQOL)...
5.
Noordman B, Wijnhoven B, Lagarde S, Biermann K, van der Gaast A, Spaander M, et al.
Dis Esophagus
. 2017 Sep;
30(12):1-8.
PMID: 28881890
Neoadjuvant chemoradiotherapy (nCRT) followed by surgery is standard of care for locally advanced esophageal cancer in many countries. After nCRT up to one third of all patients have a pathologically...
6.
Markar S, Noordman B, MacKenzie H, Findlay J, Boshier P, Ni M, et al.
Ann Oncol
. 2017 Jan;
28(3):519-527.
PMID: 28039180
Background: The primary aim of this study was to compare survival from neoadjuvant chemoradiotherapy plus surgery (NCRS) versus neoadjuvant chemotherapy plus surgery (NCS) for the treatment of esophageal or junctional...
7.
Shapiro J, van Klaveren D, Lagarde S, Toxopeus E, van der Gaast A, Hulshof M, et al.
Br J Surg
. 2016 Apr;
103(8):1039-47.
PMID: 27115731
Background: The value of conventional prognostic factors is unclear in the era of multimodal treatment for oesophageal cancer. This study aimed to quantify the impact of neoadjuvant chemoradiotherapy (nCRT) and...
8.
Toxopeus E, Talman S, van der Gaast A, Spaander V, van Rij C, Krak N, et al.
Eur J Surg Oncol
. 2014 Dec;
41(3):323-32.
PMID: 25534280
Background: Patients with locoregionally advanced oesophageal tumours or disputable distant metastases are referred for induction chemotherapy with the aim to downstage the tumour before an oesophagectomy is considered. Study Design:...
9.
Eskens F, Tresca P, Tosi D, van Doorn L, Fontaine H, van der Gaast A, et al.
Br J Cancer
. 2014 Apr;
110(9):2170-7.
PMID: 24714750
Background: The vascular disrupting agent ombrabulin shows synergy with docetaxel in vivo. Recommended phase II doses were determined in a dose escalation study in advanced solid tumours. Methods: Ombrabulin (30-min...
10.
van Hagen P, Hulshof M, van Lanschot J, Steyerberg E, van Berge Henegouwen M, Wijnhoven B, et al.
N Engl J Med
. 2012 Jun;
366(22):2074-84.
PMID: 22646630
Background: The role of neoadjuvant chemoradiotherapy in the treatment of patients with esophageal or esophagogastric-junction cancer is not well established. We compared chemoradiotherapy followed by surgery with surgery alone in...