» Authors » A T Brunger

A T Brunger

Explore the profile of A T Brunger including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 110
Citations 14004
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Fenn T, Schnieders M, Brunger A
Acta Crystallogr D Biol Crystallogr . 2010 Sep; 66(Pt 9):1024-31. PMID: 20823553
Inclusion of low-resolution data in macromolecular crystallography requires a model for the bulk solvent. Previous methods have used a binary mask to accomplish this, which has proven to be very...
2.
Gleick P, ADAMS R, Amasino R, Anders E, Anderson D, Anderson W, et al.
Science . 2010 May; 328(5979):689-90. PMID: 20448167
No abstract available.
3.
Brunger A, Jin R, Breidenbach M
Cell Mol Life Sci . 2008 Apr; 65(15):2296-306. PMID: 18425411
Despite its extreme toxicity, botulinum neurotoxin is widely utilized in low doses as a treatment for several neurological disorders; higher doses cause the neuroparalytic syndrome botulism. The toxin blocks neurotransmitter...
4.
Tavares G, Panepucci E, Brunger A
Mol Cell . 2002 Jan; 8(6):1313-25. PMID: 11779506
PSD-95/SAP90 is a member of the MAGUK superfamily. In excitatory synapses, PSD-95 clusters receptors and ion channels at specific sites in the postsynaptic membrane and organizes downstream signaling and cytoskeletal...
5.
Brunger A
Annu Rev Biophys Biomol Struct . 2001 May; 30:157-71. PMID: 11340056
The fusion of vesicles with target membranes is controlled by a complex network of protein-protein and protein-lipid interactions. Structures of the SNARE complex, synaptotagmin III, nSec1, domains of the NSF...
6.
Brunger A
Curr Opin Struct Biol . 2001 Apr; 11(2):163-73. PMID: 11297924
The fusion of vesicles with target membranes is controlled by a complex network of protein-protein and protein-lipid interactions. Recently determined structures of the SNARE complex, synaptotagmin III, nSec1, domains of...
7.
Zhou F, Merianos H, Brunger A, Engelman D
Proc Natl Acad Sci U S A . 2001 Feb; 98(5):2250-5. PMID: 11226225
Although many polar residues are directly involved in transmembrane protein functions, the extent to which they contribute to more general structural features is still unclear. Previous studies have demonstrated that...
8.
Willis M, Bishop B, Regan L, Brunger A
Structure . 2001 Feb; 8(12):1319-28. PMID: 11188696
Background: Rop is an RNA binding, dimeric, four-helix bundle protein with a well-defined, regular hydrophobic core ideally suited for redesign studies. A family of Rop variants in which the hydrophobic...
9.
Stroupe C, Brunger A
J Mol Biol . 2000 Dec; 304(4):585-98. PMID: 11099382
We have determined crystal structures of Sec4, a member of the Rab family in the G protein superfamily, in two states: bound to GDP, and to a non-hydrolyzable GTP analog,...
10.
Rice L, Earnest T, Brunger A
Acta Crystallogr D Biol Crystallogr . 2000 Oct; 56(Pt 11):1413-20. PMID: 11053839
Multiwavelength anomalous diffraction (MAD) phasing has become a routinely used tool for determining new macromolecular structures. The MAD method has stringent data-collection requirements, typically necessitating radiation-resistant crystals and access to...