A Sivarajah
Overview
Explore the profile of A Sivarajah including associated specialties, affiliations and a list of published articles.
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Articles
11
Citations
280
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Recent Articles
1.
Sivarajah A, Collins S, Sutton M, Regan N, West H, Holbrook M, et al.
J Pharmacol Toxicol Methods
. 2010 Jun;
62(1):12-9.
PMID: 20570743
Introduction: ICH S7A and S7B guidelines recommend the use of conscious animals for assessment of non-clinical cardiovascular safety of new chemical entities prior to testing in humans. Protocol design and...
2.
Sivarajah A, McDonald M, Thiemermann C
Shock
. 2006 Aug;
26(2):154-61.
PMID: 16878023
We investigated whether (endogenous) hydrogen sulfide (H2S) protects the heart against myocardial ischemia and reperfusion injury. Furthermore, we investigated whether endogenous H2S is involved in the protection afforded by (1)...
3.
Clawson G, Miranda G, Sivarajah A, Xin P, Pan W, Thiboutot D, et al.
Gene Ther
. 2004 Jul;
11(17):1331-41.
PMID: 15229628
Human papillomaviruses (HPVs) are recognized as important human pathogens, causing a spectrum of hyperproliferative lesions from benign warts to cervical dysplasias/carcinomas. HPV-associated lesions require continued production of the oncogenic E6/E7...
4.
Thiboutot D, Sivarajah A, Gilliland K, Cong Z, CLAWSON G
J Invest Dermatol
. 2000 Sep;
115(4):614-9.
PMID: 10998132
Melanocortins regulate pigmentation, adrenal hormone secretion, immune functions, lipid metabolism, and feeding behaviors in rodents. These peptides include adrenocorticotrophic hormone, melanocyte stimulating hormone, beta-lipotrophin, and the endorphins. Lipid metabolism in...
5.
Tabibzadeh S, Sivarajah A, Carpenter D, Ohlsson-Wilhelm B, Satyaswaroop P
J Clin Endocrinol Metab
. 1990 Sep;
71(3):740-7.
PMID: 2203800
Both ultrapure human interleukin-1 (IL-1) and Escherichia coli derived recombinant IL-1 alpha and beta consistently induced the expression of major histocompatibility class II (HLA-DR) molecules in a human endometrial and...
6.
Taylor A, Sivarajah A, Kelly D, Lewis Jr G
Mil Med
. 1986 Aug;
151(8):442-5.
PMID: 3093929
No abstract available.
7.
Murad S, Sivarajah A, Pinnell S
Connect Tissue Res
. 1985 Jan;
13(2):181-6.
PMID: 2985330
In the absence of ascorbic acid, confluent human skin fibroblasts incubated in 0.5% serum-supplemented medium had one-third of the level of lysyl hydroxylase activity of cells incubated in media containing...
8.
Murad S, Sivarajah A, Pinnell S
Biochem Biophys Res Commun
. 1981 Aug;
101(3):868-75.
PMID: 6272771
No abstract available.
9.
Murad S, Grove D, Lindberg K, Reynolds G, Sivarajah A, Pinnell S
Proc Natl Acad Sci U S A
. 1981 May;
78(5):2879-82.
PMID: 6265920
After prolonged exposure to ascorbate, collagen synthesis in cultured human skin fibroblasts increased approximately 8-fold with no significant change in synthesis of noncollagen protein. This effect of ascorbate appears to...
10.
Freiberger H, Grove D, Sivarajah A, Pinnell S
J Invest Dermatol
. 1980 Nov;
75(5):425-30.
PMID: 7430711
Human skin fibroblast culture promises to be a useful system for the investigation of the regulation of collagen biosynthesis and the study of abnormalities in collagen biosynthesis in connective tissue...