A Seeringer
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Explore the profile of A Seeringer including associated specialties, affiliations and a list of published articles.
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7
Citations
87
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Recent Articles
1.
Seeringer A, Bartelheim K, Kerl K, Hasselblatt M, Leuschner I, Rutkowski S, et al.
Klin Padiatr
. 2014 Mar;
226(3):143-8.
PMID: 24633978
Rhabdoid tumors mainly affect infants and other very young children with a marked vulnerability towards intensive therapy such as invasive surgery, high dose chemotherapy (HDCT) and dose intense radiotherapy. Radiotherapy...
2.
Parmar S, Schumann C, Rudiger S, Boeck S, Heinemann V, Kachele V, et al.
Pharmacogenomics J
. 2011 Dec;
13(2):181-8.
PMID: 22158333
The aim of this study was to investigate pharmacogenetic determinants of skin rash associated with epidermal growth factor receptor (EGFR) inhibitor treatment. A total of 109 prospectively sampled cancer patients,...
3.
Seeringer A, Parmar S, Fischer A, Altissimo B, Zondler L, Lebedeva E, et al.
Diabetes Obes Metab
. 2010 Oct;
12(12):1106-12.
PMID: 20977583
Aim: The therapeutic efficacy of oral hypoglycaemic drugs varies between individuals, and pharmacogenetic factors contribute to this variability. The Gly972Arg polymorphism in the insulin receptor substrate-1 (IRS-1) has been shown...
4.
Kirchheiner J, Seeringer A, Godoy A, Ohmle B, Maier C, Beschoner P, et al.
Mol Psychiatry
. 2010 Apr;
16(3):237, 333-41.
PMID: 20368706
The cytochrome P450 2D6 (CYP2D6) is a genetically polymorphic enzyme involved in the metabolism of several psychoactive drugs. Beside its expression in the liver, CYP2D6 is highly expressed in several...
5.
Seeringer A, Kirchheiner J
Internist (Berl)
. 2008 Jun;
49(7):877-83.
PMID: 18551264
The efficacy of a drug therapy is influenced by many different factors such as age, weight, comorbidity and co-medication, which vary between patients, as well as fixed parameters such as...
6.
Wyen C, Fuhr U, Frank D, Aarnoutse R, Klaassen T, Lazar A, et al.
Clin Pharmacol Ther
. 2008 Jan;
84(1):75-82.
PMID: 18183034
This study aimed to quantify the inhibition of cytochrome P450 (CYP3A), CYP2D6, and P-glycoprotein in human immunodeficiency virus (HIV)-infected patients receiving an antiretroviral therapy (ART) containing ritonavir boosted lopinavir, and...
7.
Kirchheiner J, Seeringer A, Brockmoller J
Bundesgesundheitsblatt Gesundheitsforschung Gesundheitsschutz
. 2006 Oct;
49(10):995-1003.
PMID: 17013776
Individual differences in the effect and side effect of drugs are partly due to genetic factors (genetic polymorphisms). The responsible polymorphisms lie in genes encoding for drug metabolism and transport...