A Scott Muerhoff
Overview
Explore the profile of A Scott Muerhoff including associated specialties, affiliations and a list of published articles.
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Articles
23
Citations
1070
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0
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Recent Articles
1.
Lin Z, Tu B, Hemken P, Muerhoff A
J Immunol Methods
. 2023 Dec;
525:113606.
PMID: 38145790
Tumor-associated glycoprotein 72 (TAG-72) is a mucin that is overexpressed heterogeneously on the surface of cancer cells, and is a potential target for immunotherapies for various cancer types. As a...
2.
Hemken P, Israeli E, Taylor R, Jacobson C, Datwyler M, Geissler R, et al.
Clin Chem Lab Med
. 2023 Feb;
61(8):1511-1517.
PMID: 36799248
Objectives: To evaluate pre-analytical challenges related to high-volume central laboratory SARS-CoV-2 antigen testing with a prototype qualitative SARS-CoV-2 antigen immunoassay run on the automated Abbott ARCHITECT instrument. Methods: Contrived positive...
3.
Israeli E, Okura H, Kreutz B, Piktel R, Hadji A, Tu B, et al.
J Immunol Methods
. 2022 Mar;
504:113262.
PMID: 35341761
Objectives: Quantitative detection of interleukin-6 (IL-6) in serum and plasma can help monitor immune responses and the development of acute inflammation to guide patient management. We developed an IL-6 immunoassay...
4.
Marohnic C, Birkenmeyer L, Bogdan M, Frias E, Otis K, Palafox M, et al.
J Virol Methods
. 2018 Nov;
264:11-17.
PMID: 30381240
Hepatitis C Virus c33, a recombinant protein comprising residues 1192-1457 of NS3 helicase, has been a mainstay of HCV serology for decades. With seven unpaired cysteines, seroreactivity of E. coli...
5.
Eng F, El-Shamy A, Doyle E, Klepper A, Muerhoff A, Branch A
Hepatol Commun
. 2018 Feb;
2(1):21-28.
PMID: 29404509
Hepatitis C virus (HCV) is one of the most prevalent causes of chronic blood-borne infections worldwide. Despite developments of highly effective treatments, most infected individuals are unaware of their infection....
6.
Smith D, Meyers G, Bukh J, Gould E, Monath T, Muerhoff A, et al.
J Gen Virol
. 2017 Aug;
98(8):2106-2112.
PMID: 28786787
We propose the creation of seven new species in the genus Pestivirus (family Flaviviridae) in addition to the four existing species, and naming species in a host-independent manner using the...
7.
Tu B, Tieman B, Moore J, Pan Y, Muerhoff A
Monoclon Antib Immunodiagn Immunother
. 2017 May;
36(3):113-118.
PMID: 28557609
Monoclonal antibodies are widely used as the capture and detection reagents in diagnostic immunoassays. In the past, myeloma fusion partners expressing endogenous heavy and/or light chains were often used to...
8.
Smith D, Becher P, Bukh J, Gould E, Meyers G, Monath T, et al.
J Gen Virol
. 2016 Oct;
97(11):2894-2907.
PMID: 27692039
Proposals are described for the assignment of recently reported viruses, infecting rodents, bats and other mammalian species, to new species within the Hepacivirus and Pegivirus genera (family Flaviviridae). Assignments into...
9.
Smith D, Bukh J, Kuiken C, Muerhoff A, Rice C, Stapleton J, et al.
Hepatology
. 2013 Oct;
59(1):318-27.
PMID: 24115039
Unlabelled: The 2005 consensus proposal for the classification of hepatitis C virus (HCV) presented an agreed and uniform nomenclature for HCV variants and the criteria for their assignment into genotypes...
10.
Hawksworth D, Tu B, Tieman B, Brophy S, Tyner J, Muerhoff A, et al.
Hybridoma (Larchmt)
. 2012 Dec;
31(6):436-42.
PMID: 23244323
Development of a robust immunoassay requires the selection of monoclonal antibodies with desired properties. These properties generally include kinetics parameters such as on-rate and off-rate (i.e., binding affinity), and, often...