A S Schaefer
Overview
Explore the profile of A S Schaefer including associated specialties, affiliations and a list of published articles.
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Articles
13
Citations
170
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Recent Articles
1.
Zheng L, Chopra A, Weiner 3rd J, Beule D, Dommisch H, Schaefer A
J Dent Res
. 2023 Oct;
102(13):1488-1497.
PMID: 37822091
Several array-based microRNA (miRNA) expression studies independently showed increased expression of miRNAs hsa-miR-130a-3p, -142-3p, -144-3p, -144-5p, -223-3p, -17-5p, and -30e-5p in gingiva affected by periodontal inflammation. We aimed to determine...
2.
Divaris K, Haworth S, Shaffer J, Anttonen V, Beck J, Furuichi Y, et al.
J Dent Res
. 2022 Aug;
101(11):1408-1416.
PMID: 36000800
Genetic risk factors play important roles in the etiology of oral, dental, and craniofacial diseases. Identifying the relevant risk loci and understanding their molecular biology could highlight new prevention and...
3.
Mueller R, Chopra A, Dommisch H, Schaefer A
J Dent Res
. 2021 Dec;
101(5):551-558.
PMID: 34852650
Periodontitis is a common complex inflammatory disease of the oral cavity. It is characterized by inflammation of gingival tissues and alveolar bone loss. Recently, a genome-wide association study and 2...
4.
Richter G, Wagner G, Reichenmiller K, Staufenbiel I, Martins O, Loscher B, et al.
J Dent Res
. 2021 Sep;
101(2):151-157.
PMID: 34515563
Periodontitis is characterized by alveolar bone loss leading to tooth loss. A small proportion of patients develop severe periodontitis at the juvenile or adolescent age without exposure to the main...
5.
Chopra A, Mueller R, Weiner 3rd J, Rosowski J, Dommisch H, Grohmann E, et al.
J Dent Res
. 2021 Jun;
101(1):93-101.
PMID: 34160287
Genome-wide association studies identified various loci associated with periodontal diseases, but assigning causal alleles remains difficult. Likewise, the generation of biological meaning underlying a statistical association has been challenging. Here,...
6.
Bao X, Weiner 3rd J, Meckes O, Dommisch H, Schaefer A
J Dent Res
. 2021 Apr;
100(7):771-776.
PMID: 33792418
The protozoan colonizes the healthy oral mucosa with a prevalence of 15%. Colonization can be asymptomatic, and it is considered not pathogenic. However, it is able to invade lacerated oral...
7.
Bao X, Wiehe R, Dommisch H, Schaefer A
J Dent Res
. 2020 Feb;
99(5):561-567.
PMID: 32023135
A metagenomics analysis showed a strongly increased frequency of the protozoan in inflamed periodontal pockets, where it contributed the second-most abundant rRNA after human rRNA. This observation and the close...
8.
Freitag-Wolf S, Munz M, Wiehe R, Junge O, Graetz C, Jockel-Schneider Y, et al.
J Dent Res
. 2019 Sep;
98(12):1332-1339.
PMID: 31537151
Periodontitis has low-prevalence, highly severe disease manifestations with an early onset and rapid progression. The diagnosis is based on severe destruction of the alveolar bone in adolescents and young adults....
9.
Aarabi G, Zeller T, Seedorf H, Reissmann D, Heydecke G, Schaefer A, et al.
J Dent Res
. 2017 May;
96(6):610-617.
PMID: 28530468
Periodontal disease (PD) and coronary artery disease (CAD) are common diseases characterized by an overaggressive inflammatory response to diverse stimuli. Whereas PD leads to destruction of the tooth-supporting structures, CAD...
10.
Shusterman A, Munz M, Richter G, Jepsen S, Lieb W, Krone B, et al.
J Dent Res
. 2017 May;
96(8):945-952.
PMID: 28467728
Periodontitis is a common dysbiotic inflammatory disease with an estimated heritability of 50%. Due to the limited sample size of available periodontitis cohorts and the underlying trait heterogeneity, genome-wide association...