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A Rostagno

Explore the profile of A Rostagno including associated specialties, affiliations and a list of published articles. Areas
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Articles 35
Citations 1054
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Recent Articles
1.
Zampar S, Klafki H, Sritharen K, Bayer T, Wiltfang J, Rostagno A, et al.
Neuropathol Appl Neurobiol . 2020 Jun; 46(7):673-685. PMID: 32497293
Aims: The deposition of amyloid-β (Aβ) peptides in the form of extracellular plaques in the brain represents one of the classical hallmarks of Alzheimer's disease (AD). In addition to 'full-length'...
2.
Fossati S, Ghiso J, Rostagno A
Cell Death Dis . 2012 Jun; 3:e321. PMID: 22695614
Vascular deposition of amyloid-β (Aβ) in sporadic and familial Alzheimer's disease, through poorly understood molecular mechanisms, leads to focal ischemia, alterations in cerebral blood flow, and cerebral micro-/macro-hemorrhages, significantly contributing...
3.
Rostagno A, Holton J, Lashley T, Revesz T, Ghiso J
Cell Mol Life Sci . 2009 Nov; 67(4):581-600. PMID: 19898742
Cerebral amyloid diseases are part of a complex group of chronic and progressive entities bracketed together under the common denomination of protein folding disorders and characterized by the intra- and...
4.
Fossati S, Cam J, Meyerson J, Mezhericher E, Romero I, Couraud P, et al.
FASEB J . 2009 Sep; 24(1):229-41. PMID: 19770225
Cerebral amyloid angiopathy (CAA) is an age-associated condition and a common finding in Alzheimer's disease in which amyloid-beta (Abeta) vascular deposits are featured in >80% of the cases. Familial Abeta...
5.
Viana R, Nunes A, Castro R, Ramalho R, Meyerson J, Fossati S, et al.
Cell Mol Life Sci . 2009 Feb; 66(6):1094-104. PMID: 19189048
The vasculotropic E22Q mutant of the amyloid-beta (Abeta) peptide is associated with hereditary cerebral hemorrhage with amyloidosis Dutch type. The cellular mechanism(s) of toxicity and nature of the AbetaE22Q toxic...
6.
Lashley T, Revesz T, Plant G, Bandopadhyay R, Lees A, Frangione B, et al.
Neuropathol Appl Neurobiol . 2008 Feb; 34(5):492-505. PMID: 18282158
Introduction: Two different disease-specific mutations in the BRI2 gene, situated on chromosome 13, have been identified as giving rise to familial British dementia (FBD) and familial Danish dementia (FDD). Each...
7.
Lashley T, Holton J, Verbeek M, Rostagno A, Bojsen-Moller M, David G, et al.
Neuropathol Appl Neurobiol . 2006 Sep; 32(5):492-504. PMID: 16972883
Molecular chaperons or amyloid-associated proteins (AAPs) are deposited in vascular and parenchymal amyloid lesions in Alzheimer's disease (AD) and other amyloidoses. AAPs, such as apolipoprotein E (ApoE) or apolipoprotein J...
8.
Ghiso J, Rostagno A, Tomidokoro Y, Lashley T, Bojsen-Moller M, Braendgaard H, et al.
Brain Pathol . 2006 Apr; 16(1):71-9. PMID: 16612984
Classic arguments sustaining the importance of amyloid in the pathogenesis of dementia are usually centered on amyloid beta (Abeta) and its role in neuronal loss characteristic of Alzheimer disease, the...
9.
Rostagno A, Tomidokoro Y, Lashley T, Ng D, Plant G, Holton J, et al.
Cell Mol Life Sci . 2005 Jun; 62(16):1814-25. PMID: 15968464
The importance of cerebral amyloid deposition in the mechanism of neurodegeneration is still debatable. Classic arguments are usually centered on amyloid beta(Abeta) and its role in the neuronal loss characteristic...
10.
Ghiso J, Revesz T, Holton J, Rostagno A, Lashley T, Houlden H, et al.
Amyloid . 2002 Jan; 8(4):277-84. PMID: 11791622
Two hereditary conditions, familial British dementia (FBD) and familial Danish dementia (FDD), are associated with amyloid deposition in the central nervous system and neurodegeneration. The two amyloid proteins, ABri and...