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A Riches

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Articles 19
Citations 132
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Recent Articles
1.
Wang H, Robinson S, Melvillej J, Riches A
Urol Oncol . 2011 Jan; 1(5):208-14. PMID: 21224120
The objective of this study was to demonstrate that a nontumorigenic simian virus 40 (SV40) immortalized human urothelial cell line can be tumorigenically transformed following growth in a serum free,...
2.
Stevenson D, Agate B, Tsampoula X, Fischer P, Brown C, Sibbett W, et al.
Opt Express . 2009 Jun; 14(16):7125-33. PMID: 19529083
Photoporation is a rapidly expanding technique for the introduction of macromolecules into single cells. However, there remains no study into the true efficiency of this procedure. Here, we present a...
3.
Jess P, Garces-Chavez V, Smith D, Mazilu M, Paterson L, Riches A, et al.
Opt Express . 2009 Jun; 14(12):5779-91. PMID: 19516747
Raman spectroscopy permits acquisition of molecular signatures from both cellular and sub-cellular samples. When combined with optical trapping we may interrogate an isolated cell reducing extraneous signals from the local...
4.
Paterson L, Agate B, Comrie M, Ferguson R, Lake T, Morris J, et al.
Opt Express . 2009 Jun; 13(2):595-600. PMID: 19488389
The introduction and subsequent expression of foreign DNA inside living mammalian cells (transfection) is achieved by photoporation with a violet diode laser. We direct a compact 405 nm laser diode...
5.
Thierry J, Grillon C, Gaudron S, Potier P, Riches A, Wdzieczak-Bakala J
J Pept Sci . 2001 Jun; 7(5):284-93. PMID: 11428549
The tetrapeptide N-Acetyl-Ser-Asp-Lys-Pro (AcSDKP), an inhibitor of haematopoietic stem cell proliferation, reduces in vivo and in vitro the damage to the stem cell compartment resulting from treatment with chemotherapeutic agents...
6.
Mulcahy H, Riches A, Kiely M, Farthing M, Fairclough P
Endoscopy . 2001 Apr; 33(4):311-6. PMID: 11315891
Background And Study Aims: Upper gastrointestinal endoscopy is performed without sedation in many countries. Unsedated patients experience more discomfort during endoscopy than sedated patients, but few studies have examined factors...
7.
Riches A, Peddie C, Rendell S, Bryant P, Zitzelsberger H, Bruch J, et al.
Radiat Res . 2000 Dec; 155(1 Pt 2):222-229. PMID: 11121238
Neoplastic transformation of human epithelial cells by radiation has previously been investigated using cell lines immortalized with viral vectors. There are disadvantages to this approach, and we report here the...
8.
Gaudron S, Grillon C, Thierry J, Riches A, Wierenga P, Wdzieczak-Bakala J
Stem Cells . 1999 Apr; 17(2):100-6. PMID: 10195570
The tetrapeptide Acetyl-N-Ser-Asp-Lys-Pro (AcSDKP), an inhibitor of hematopoietic stem cell proliferation, is known to reduce in vivo the damage resulting from treatment with chemotherapeutic agents or ionizing radiation on the...
9.
Wdzieczak-Bakala J, Lenfant M, Ezan E, Genet R, Robinson S, Briscoe T, et al.
Exp Hematol . 1998 Oct; 26(11):1074-9. PMID: 9766448
The hemoregulatory peptide N-Acetyl-Ser-Asp-Lys-Pro (AcSDKP) has been shown in vivo to inhibit the cycling of murine hematopoietic stem cells triggered into S-phase by either cytotoxic drug administration or irradiation. This...
10.
Riches A, Herceg Z, Wang H, Bryant P, Armitage M, GAMBLE S, et al.
Radiat Oncol Investig . 1997 Jan; 5(3):139-43. PMID: 9303072
It has proved difficult to develop suitable models to study radiation-induced carcinogenesis by using human epithelial cells. However, immortalised human epithelial cell lines have proved useful. Unirradiated cells from the...