» Authors » A R Shikhman

A R Shikhman

Explore the profile of A R Shikhman including associated specialties, affiliations and a list of published articles. Areas
Snapshot
Articles 37
Citations 319
Followers 0
Related Specialties
Top 10 Co-Authors
Published In
Affiliations
Soon will be listed here.
Recent Articles
1.
Shikhman A, Brinson D, Valbracht J, Lotz M
Osteoarthritis Cartilage . 2009 Apr; 17(8):1022-8. PMID: 19332174
Objective: Aminosugars are commonly used to treat osteoarthritis; however, molecular mechanisms mediating their anti-arthritic activities are still poorly understood. This study analyzes facilitated transport and metabolic effects of glucosamine (GlcN)...
2.
Shikhman A, Amiel D, DLima D, Hwang S, Hu C, Xu A, et al.
Ann Rheum Dis . 2004 Dec; 64(1):89-94. PMID: 15608304
Objective: To examine the therapeutic efficacy of N-acetylglucosamine (GlcNAc) in rabbits with experimental osteoarthritis (OA). Methods: Experimental OA was induced in rabbits by anterior cruciate ligament transection (ACLT). In the...
3.
Shikhman A, Brinson D, Valbracht J, Lotz M
J Immunol . 2001 Dec; 167(12):7001-8. PMID: 11739520
Glucose serves as the major energy substrate and the main precursor for the synthesis of glycosaminoglycans in chondrocytes. Facilitated glucose transport represents the first rate-limiting step in glucose metabolism. This...
4.
Liu J, Shikhman A, Lotz M, Wong C
Chem Biol . 2001 Jul; 8(7):701-11. PMID: 11451670
Background: Articular cartilage from patients with osteoarthritis is characterized by a decreased concentration and reduced size of glycosaminoglycans. Degeneration of the cartilage matrix is a multifactorial process, which is due...
5.
Shikhman A, Kuhn K, Alaaeddine N, Lotz M
J Immunol . 2001 Apr; 166(8):5155-60. PMID: 11290798
Glucosamine represents one of the most commonly used drugs to treat osteoarthritis. However, mechanisms of its antiarthritic activities are still poorly understood. The present study identifies a novel mechanism of...
6.
Shikhman A, Brinson D, Lotz M
Arthritis Rheum . 2000 Jun; 43(6):1307-14. PMID: 10857789
Objective: To determine enzymatic activities of the 8 key glycosaminoglycan-degrading glycosidases and glycoside sulfatases in cultured human articular chondrocytes and in synovial fluid from patients with osteoarthritis. Methods: The following...
7.
Adderson E, Shikhman A, Ward K, Cunningham M
J Immunol . 1998 Aug; 161(4):2020-31. PMID: 9712075
Anti-myosin Abs are associated with inflammatory heart diseases such as rheumatic carditis and myocarditis. In this study, human cross-reactive anti-streptococcal/anti-myosin mAbs 1.C8, 1.H9, 5.G3, and 3.B6, produced from peripheral blood...
8.
Demarco P, Schulman S, Shikhman A
N Engl J Med . 1998 Aug; 339(5):350-1. PMID: 9696652
No abstract available.
9.
Shikhman A, Cunningham M
Nat Biotechnol . 1997 Jun; 15(6):512-3. PMID: 9181569
No abstract available.
10.
CHERKASOV V, Anokhina G, Shikhman A, Briko N
Klin Med (Mosk) . 1995 Jan; 73(4):97-8. PMID: 7474846
No abstract available.