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A R Coates

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Articles 58
Citations 794
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Recent Articles
1.
Steptoe A, Shamaei-Tousi A, Gylfe A, Bailey L, Bergstrom S, Coates A, et al.
Clin Vaccine Immunol . 2007 Jan; 14(2):204-7. PMID: 17202307
The presence of heat shock protein 60 (Hsp60) in human plasma has been linked with cardiovascular disease (CVD). In this study, the examination of the relationship between Hsp60 in plasma...
2.
Hu Y, Coates A, Mitchison D
Int J Tuberc Lung Dis . 2006 Mar; 10(3):317-22. PMID: 16562713
Setting: Pyrazinamide (PZA) is an effective sterilising drug in tuberculosis, but its mode of action is controversial. Objective: To test the bactericidal activity of 1.56-100 microg/ml PZA in Hu/Coates models...
3.
Ranford J, Coates A, Henderson B
Expert Rev Mol Med . 2003 Oct; 2(8):1-17. PMID: 14585136
The chaperonins are a subgroup of oligomeric molecular chaperones; the best-studied examples are chaperonin 60 (GroEL) and chaperonin 10 (GroES), both from the bacterium Escherichia coli. At the end of...
4.
Lewthwaite J, Coates A, Tormay P, Singh M, Mascagni P, Poole S, et al.
Infect Immun . 2001 Nov; 69(12):7349-55. PMID: 11705907
Much attention has focused on the Mycobacterium tuberculosis molecular chaperone chaperonin (Cpn) 60.2 (Hsp 65) in the pathology of tuberculosis because of its immunogenicity and ability to directly activate human...
5.
Hu Y, Coates A
FEMS Microbiol Lett . 2001 Aug; 202(1):59-65. PMID: 11506908
In order to determine which genes are involved in maintaining viability of 100-day stationary-phase bacteria and persistent bacteria after antibiotic treatment, we used a mini-DNA array to examine the transcription...
6.
Hu Y, Mangan J, Dhillon J, Sole K, Mitchison D, Butcher P, et al.
J Bacteriol . 2000 Oct; 182(22):6358-65. PMID: 11053379
Mycobacterium tuberculosis can persist in an altered physiological state for many years after initial infection, and it may reactivate to cause active disease. An analogous persistent state, possibly consisting of...
7.
Coates A, Henderson B, Mascagni P
Biotechnol Genet Eng Rev . 2000 May; 16:393-405. PMID: 10819086
No abstract available.
8.
Rosenkrands I, Weldingh K, Ravn P, Brandt L, Hojrup P, Rasmussen P, et al.
Infect Immun . 1999 Oct; 67(11):5552-8. PMID: 10531199
Mycobacterium tuberculosis GroES was purified from culture filtrate, and its identity was confirmed by immunoblot analysis and N-terminal sequencing. Comparing the immunological recognition of native and recombinant GroES, we found...
9.
Hu Y, Butcher P, Mangan J, Rajandream M, Coates A
J Bacteriol . 1999 May; 181(11):3486-93. PMID: 10348862
The Mycobacterium tuberculosis hmp gene encodes a protein which is homologous to flavohemoglobin in Escherichia coli. Northern blotting analysis demonstrated that hmp transcription increased when a microaerophilic culture became oxygen...
10.
Roberts M, Coker A, Fossati G, Mascagni P, Coates A, Wood S
Acta Crystallogr D Biol Crystallogr . 1999 Mar; 55(Pt 4):910-4. PMID: 10089332
The Mycobacterium tuberculosis chaperonin 10 (Mtcpn10) has been crystallized by the sitting-drop vapour-diffusion method. The crystals belong to the monoclinic space group P21, with unit-cell parameters a = 76.5, b...