A Premawardhena
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Explore the profile of A Premawardhena including associated specialties, affiliations and a list of published articles.
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11
Citations
198
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Recent Articles
1.
Fejzo M, Rocha N, Cimino I, Lockhart S, Petry C, Kay R, et al.
Nature
. 2023 Dec;
625(7996):760-767.
PMID: 38092039
GDF15, a hormone acting on the brainstem, has been implicated in the nausea and vomiting of pregnancy, including its most severe form, hyperemesis gravidarum (HG), but a full mechanistic understanding...
2.
Fejzo M, Rocha N, Cimino I, Lockhart S, Petry C, Kay R, et al.
bioRxiv
. 2023 Jul;
PMID: 37398065
Human pregnancy is frequently accompanied by nausea and vomiting that may become severe and life-threatening, as in hyperemesis gravidarum (HG), the cause of which is unknown. Growth Differentiation Factor-15 (GDF15),...
3.
Premawardhena A, Perera P
Ceylon Med J
. 2018 Nov;
63(3):105-107.
PMID: 30415512
No abstract available.
4.
Balasooriya B, Fonseka H, Williams S, Premawardhena A
Ceylon Med J
. 2010 Jan;
54(4):131-2.
PMID: 20052857
No abstract available.
5.
ODonnell A, Premawardhena A, Arambepola M, Samaranayake R, Allen S, Peto T, et al.
Proc Natl Acad Sci U S A
. 2009 Oct;
106(44):18716-21.
PMID: 19841268
In many Asian populations, the commonest form of severe thalassemia results from the coinheritance of HbE and beta thalassemia. The management of this disease is particularly difficult because of its...
6.
Premawardhena A, Arambepola M, Katugaha N, Weatherall D
Br J Haematol
. 2008 Mar;
141(3):407-10.
PMID: 18341640
Although the beta thalassaemia trait affects millions of people worldwide, there have been no controlled studies to determine whether it is associated with any clinical disability or abnormal physical signs....
7.
ODonnell A, Premawardhena A, Arambepola M, Allen S, Peto T, Fisher C, et al.
Proc Natl Acad Sci U S A
. 2007 May;
104(22):9440-4.
PMID: 17517643
Severe forms of anemia in children in the developing countries may be characterized by different clinical manifestations at particular stages of development. Whether this reflects developmental changes in adaptation to...
8.
Premawardhena A, Fisher C, Olivieri N, De Silva S, Arambepola M, Perera W, et al.
Lancet
. 2005 Oct;
366(9495):1467-70.
PMID: 16243092
Haemoglobin E beta thalassaemia is the commonest form of severe thalassaemia in many Asian countries, but little is known about its natural history, the reasons for clinical diversity, or its...
9.
Premawardhena A, Fisher C, Liu Y, Verma I, De Silva S, Arambepola M, et al.
Blood Cells Mol Dis
. 2003 Jul;
31(1):98-101.
PMID: 12850492
The promoter region of the UDP glucuronosyltransferase 1 gene (UGT1A1) contains a run of thymine-adenine (TA) repeats, usually six (TA)(6). As well as its relationship to Gilbert's syndrome, homozygosity for...
10.
Premawardhena A, Fisher C, Fathiu F, De Silva S, Perera W, Peto T, et al.
Lancet
. 2001 Jun;
357(9272):1945-6.
PMID: 11425418
Chronic hyperbilirubinaemia, gallstone formation, and gall bladder disease are unusually common in people with haemoglobin E beta thalassaemia in Sri Lanka. To determine whether this has a genetic basis we...