A P Feinberg
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Explore the profile of A P Feinberg including associated specialties, affiliations and a list of published articles.
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90
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14404
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Recent Articles
1.
Abante J, Fang Y, Feinberg A, Goutsias J
Nat Commun
. 2020 Oct;
11(1):5238.
PMID: 33067439
In heterozygous genomes, allele-specific measurements can reveal biologically significant differences in DNA methylation between homologous alleles associated with local changes in genetic sequence. Current approaches for detecting such events from...
2.
Feinberg A
J Intern Med
. 2014 Mar;
276(1):5-11.
PMID: 24635672
The aim of this review is to summarize an evolution of thinking about the epigenetic basis of human cancer, from the earliest studies of altered DNA methylation in cancer to...
3.
Ladd-Acosta C, Hansen K, Briem E, Fallin M, Kaufmann W, Feinberg A
Mol Psychiatry
. 2013 Sep;
19(8):862-71.
PMID: 23999529
Autism spectrum disorders (ASD) are increasingly common neurodevelopmental disorders defined clinically by a triad of features including impairment in social interaction, impairment in communication in social situations and restricted and...
4.
Kim K, Doi A, Wen B, Ng K, Zhao R, Cahan P, et al.
Nature
. 2010 Jul;
467(7313):285-90.
PMID: 20644535
Somatic cell nuclear transfer and transcription-factor-based reprogramming revert adult cells to an embryonic state, and yield pluripotent stem cells that can generate all tissues. Through different mechanisms and kinetics, these...
5.
Mirsaidov U, Timp W, Zou X, Dimitrov V, Schulten K, Feinberg A, et al.
Biophys J
. 2009 Feb;
96(4):L32-4.
PMID: 19217843
Methylation of cytosine is a covalent modification of DNA that can be used to silence genes, orchestrating a myriad of biological processes including cancer. We have discovered that a synthetic...
6.
Feinberg A
Cold Spring Harb Symp Quant Biol
. 2006 Jul;
70:335-41.
PMID: 16869770
In over 20 years since the discovery of altered methylation in cancer, many epigenetic alterations have been found in human cancer, including global and specific gene hypomethylation, hypermethylation, altered chromatin...
7.
Bjornsson H, Cui H, Gius D, Fallin M, Feinberg A
Cold Spring Harb Symp Quant Biol
. 2005 Aug;
69:447-56.
PMID: 16117680
No abstract available.
8.
Jouvenot Y, Ginjala V, Zhang L, Liu P, Oshimura M, Feinberg A, et al.
Gene Ther
. 2003 Mar;
10(6):513-22.
PMID: 12621455
Epigenetic control of transcription is essential for mammalian development and its deregulation causes human disease. For example, loss of proper imprinting control at the IGF2-H19 domain is a hallmark of...
9.
Ravenel J, Broman K, Perlman E, Niemitz E, Jayawardena T, BELL D, et al.
J Natl Cancer Inst
. 2001 Nov;
93(22):1698-703.
PMID: 11717330
Background: Loss of imprinting (LOI) of the insulin-like growth factor-II (IGF2) gene, an epigenetic alteration associated with expression of the normally silent maternal allele, was observed first in Wilms tumor....
10.
Cui H, Niemitz E, Ravenel J, Onyango P, Brandenburg S, Lobanenkov V, et al.
Cancer Res
. 2001 Jun;
61(13):4947-50.
PMID: 11431321
Loss of imprinting (LOI) is the most common molecular abnormality in Wilms' tumor (WT), other embryonal cancers, and most other tumor types. LOI in WT involves activation of the normally...