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A P Callahan

Explore the profile of A P Callahan including associated specialties, affiliations and a list of published articles. Areas
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1.
Kropp J, Knapp Jr F, Weyenberg A, McPherson D, Ambrose K, Callahan A, et al.
Eur J Nucl Med . 1994 Nov; 21(11):1227-30. PMID: 7859776
A new iodine-131-labeled triglyceride analogue called "MIPAG" [1,2-dipalmitoyl-3-[(15-p-iodophenyl) pentadecan-1-oyl]rac-glycerol] has been prepared in which 15-(p-iodophenyl)pentadecanoic acid (IPPA) is attached to position-3. MIPAG has been developed for the evaluation of pancreatic...
2.
Knapp Jr F, Kropp J, McPherson D, Ambrose K, Lambert C, Callahan A, et al.
J Nucl Med . 1993 Jun; 34(6):946-52. PMID: 8509862
To measure pancreatic lipase activity, we synthesized a triglyceride containing a radioiodinated fatty acid. The urinary excretion of radioactivity was measured in five rats following administration of the agent by...
3.
McPherson D, Dehaven-Hudkins D, Callahan A, Knapp Jr F
J Med Chem . 1993 Apr; 36(7):848-54. PMID: 8464039
1-Azabicyclo[2.2.2]oct-3-yl alpha-hydroxy-alpha-(1-iodo-1-propen-3-yl)- alpha-phenylacetate (IQNP, 3), an analogue of QNB in which a phenyl ring has been replaced with an iodopropenyl substituent, was prepared and evaluated in vitro and in vivo...
4.
Singh J, Reghebi K, Lazarus C, Clarke S, Callahan A, Knapp Jr F, et al.
Nucl Med Commun . 1993 Mar; 14(3):197-203. PMID: 8384352
The preparative conditions for 186Re(V)DMSA and 188Re(V)DMSA (DMSA = meso-dimercaptosuccinic acid), beta-emitting radiopharmaceuticals that have been shown to localize in medullary thyroid carcinoma, require modification depending on the amount of...
5.
Griffiths G, Goldenberg D, Knapp Jr F, Callahan A, Chang C, Hansen H
Cancer Res . 1991 Sep; 51(17):4594-602. PMID: 1873804
The use of 188Re from an alumina-based 188W/188Re generator has been investigated for antibody radiolabeling. It was found that, with simple labeling techniques, 188Re can be used immediately after elution....
6.
Ambrose K, Owen B, Callahan A, Goodman M, Knapp Jr F
Int J Rad Appl Instrum B . 1988 Jan; 15(6):695-700. PMID: 3251902
The myocardial lipid pool distribution and subcellular distribution of radiolabeled methyl-branched fatty acids in rats was evaluated under conditions of fasting (24 h) and feeding. With the unbranched iodophenyl fatty...
7.
Knapp Jr F, Goodman M, Callahan A, Kirsch G
J Nucl Med . 1986 Apr; 27(4):521-31. PMID: 3712065
Radioiodinated 15-(p-iodophenyl)-3,3-dimethylpentadecanoic acid (DMIPP) has been prepared as a new terminal iodophenyl-substituted fatty acid containing dimethyl-branching at the beta position. For the synthesis of this new agent, chain homologation was...
8.
Goodman M, Callahan A, Knapp Jr F
J Med Chem . 1985 Jun; 28(6):807-15. PMID: 4009604
The synthesis of a new methyl-branched fatty acid, (E)-19-iodo-3(RS)-methyl-18-nonadecenoic acid (19), is described. Methyl branching has been introduced at the 3-position to inhibit beta-oxidation and radioiodide has been attached as...
9.
Srivastava P, Knapp Jr F, Callahan A, Owen B, Kabalka G, Sastry K
J Med Chem . 1985 Apr; 28(4):408-13. PMID: 3981533
The effects of replacement of radioiodide with radiobromide on the biological properties of a model vinyl halide substituted tellurium fatty acid have been evaluated. The use of a facile radiobromination...
10.
Knapp Jr F, Srivastava P, Callahan A, Cunningham E, Kabalka G, Sastry K
J Med Chem . 1984 Jan; 27(1):57-63. PMID: 6690683
The effect of tellurium (Te) position on myocardial specificity and retention of fatty acids in which radioiodide is stabilized as a trans-(E)-vinyl iodide has been evaluated in rats. Five analogues...