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A Ortiz-Pelaez

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Articles 17
Citations 251
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Recent Articles
1.
Beck S, Gunawardena P, Horton D, Hicks D, Marston D, Ortiz-Pelaez A, et al.
BMC Vet Res . 2017 Apr; 13(1):99. PMID: 28403882
Background: The recommended screening of rabies in 'suspect' animal cases involves testing fresh brain tissue. The preservation of fresh tissue however can be difficult under field conditions and formalin fixation...
2.
Marier E, Dawson M, Simmons M, Hope J, Ortiz-Pelaez A
Vet Rec . 2017 Feb; 180(16):403. PMID: 28213529
A case-control study was conducted in 2013 to investigate the use of pituitary-derived hormones from sheep as a potential risk factor for the presence of atypical scrapie in Great Britain...
3.
Georgiadou S, Ortiz-Pelaez A, Simmons M, Windl O, Dawson M, Neocleous P, et al.
Epidemiol Infect . 2016 Oct; 145(2):326-328. PMID: 27751198
The results of the study reported here are part of an ongoing integrated research programme aimed at producing additional, robust, evidence on the genetic resistance to classical scrapie in goats,...
4.
Ortiz-Pelaez A, Arnold M, Vidal-Diez A
Epidemiol Infect . 2016 Mar; 144(10):2107-16. PMID: 26976340
Multiple cases of atypical scrapie in the same holding and co-existence with classical scrapie have been reported in Great Britain. A two-stage simulation tool was developed by combining a sampling...
5.
Goldmann W, Marier E, Stewart P, Konold T, Street S, Langeveld J, et al.
Vet Rec . 2016 Jan; 178(7):168. PMID: 26755614
Scrapie in goats is a transmissible, fatal prion disease, which is endemic in the British goat population. The recent success in defining caprine PRNP gene variants that provide resistance to...
6.
Ortiz-Pelaez A, Georgiadou S, Simmons M, Windl O, Dawson M, Arnold M, et al.
Epidemiol Infect . 2014 Aug; 143(6):1304-10. PMID: 25140573
Previous studies have shown the association between the polymorphisms serine (S) or aspartic acid (D) at codon 146 of the PRNP gene and resistance to scrapie. All goats aged >12...
7.
Ortiz-Pelaez A, Thompson C, Dawson M
Vet Rec . 2014 Apr; 174(21):530. PMID: 24696442
In order to determine the PRNP genotype distribution of the sheep population and to assess the impact of the National Scrapie Plan, a total of 9972 brain samples were collected...
8.
Garcia-Jimenez W, Salguero F, Fernandez-Llario P, Martinez R, Risco D, Gough J, et al.
Vet Immunol Immunopathol . 2013 Oct; 156(1-2):54-63. PMID: 24144683
Limited information has been published on the wild boar immune response against bovine tuberculosis (bTB) and the immunopathogenesis of the pathological hallmark (granuloma) in this species. The main objectives of...
9.
Hicks D, Nunez A, Banyard A, Williams A, Ortiz-Pelaez A, Fooks A, et al.
J Comp Pathol . 2013 Jun; 149(4):446-62. PMID: 23746482
The hallmark of lyssavirus infection is lethal encephalomyelitis. Previous studies have reported distinct lyssavirus isolate-related differences in severity of cellular recruitment into the encephalon in a murine model of infection...
10.
Aranday-Cortes E, Bull N, Villarreal-Ramos B, Gough J, Hicks D, Ortiz-Pelaez A, et al.
Transbound Emerg Dis . 2012 Aug; 60(6):525-37. PMID: 22909117
To gain further insight into the immunopathogenesis of bovine tuberculosis (bTB), the cytokine and chemokine expression of cattle experimentally infected with Mycobacterium bovis was analysed in TB granulomas, using immunohistochemistry...