A N Schweitzer
Overview
Explore the profile of A N Schweitzer including associated specialties, affiliations and a list of published articles.
Author names and details appear as published. Due to indexing inconsistencies, multiple individuals may share a name, and a single author may have variations. MedLuna displays this data as publicly available, without modification or verification
Snapshot
Snapshot
Articles
16
Citations
1499
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
Published In
Published In
Affiliations
Affiliations
Soon will be listed here.
Recent Articles
1.
Schweitzer A, Sharpe A
J Immunol
. 1999 Oct;
163(9):4819-25.
PMID: 10528182
We have used T cells from B7-1-deficient TCR transgenic DO11.10 mice to demonstrate a functional role for B7-1 on T cells. B7-1-deficient DO11.10 T cells produce more IL-4 than wild-type...
2.
McAdam A, Schweitzer A, Sharpe A
Immunol Rev
. 1998 Dec;
165:231-47.
PMID: 9850864
The functional significance of B7 co-stimulation in T-cell activation was described first in the context of preventing the induction of anergy. The functions of this pathway are far more complex...
3.
Schweitzer A, Sharpe A
J Immunol
. 1998 Sep;
161(6):2762-71.
PMID: 9743334
The differentiation of CD4+ T cells into a Th1 vs Th2 phenotype profoundly influences the outcome of autoimmune and infectious diseases. B7 costimulation has been shown to affect the production...
4.
Van Parijs L, Sethna M, Schweitzer A, Borriello F, Sharpe A, Abbas A
J Immunol
. 1998 Apr;
159(11):5336-44.
PMID: 9548473
T cell activation and tolerance are regulated by interactions between CD28 or CTLA-4 on T cells and B7 costimulatory molecules on APCs. We have generated transgenic mouse strains that constitutively...
5.
Schweitzer A, Sharpe A
Agents Actions Suppl
. 1998 Jan;
49:33-43.
PMID: 9426826
There have been significant recent advances in our understanding of the role of the B7-CD28/CTLA-4 costimulatory pathway in T-cell activation and self-tolerance. Recent studies have begun to clarify how signaling...
6.
Schweitzer A, Borriello F, Wong R, Abbas A, Sharpe A
J Immunol
. 1997 Mar;
158(6):2713-22.
PMID: 9058805
For T cells to be optimally activated, recognition of Ag/MHC complexes by the TCR must be accompanied by a second, costimulatory signal that can be provided efficiently by the related...
7.
Borriello F, Sethna M, Boyd S, Schweitzer A, Tivol E, Jacoby D, et al.
Immunity
. 1997 Mar;
6(3):303-13.
PMID: 9075931
Humoral immune responses were characterized in mouse strains lacking either or both B7 molecules. Mice deficient in both B7-1 and B7-2 failed to generate antigen-specific IgG1 and IgG2a responses and...
8.
Tivol E, Schweitzer A, Sharpe A
Curr Opin Immunol
. 1996 Dec;
8(6):822-30.
PMID: 8994862
The past year has seen significant advances in our understanding of the role of the B7-CD28/CTLA-4 pathway in T cell activation and self-tolerance. Recent studies have demonstrated that CTLA-4 is...
9.
Tivol E, Borriello F, Schweitzer A, Lynch W, Bluestone J, Sharpe A
Immunity
. 1995 Nov;
3(5):541-7.
PMID: 7584144
The B7-CD28/CTLA-4 costimulatory pathway can provide a signal pivotal for T cell activation. Signaling through this pathway is complex due to the presence of two B7 family members, B7-1 and...
10.
Swinton J, Schweitzer A, Anderson R
J Theor Biol
. 1994 Jul;
169(1):23-30.
PMID: 7934072
Much work on the induction of non-responsiveness in lymphocytes suggests that it takes two signals to activate a cell correctly, and that receipt of the first signal alone not only...