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A Mottok

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Articles 9
Citations 170
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Recent Articles
1.
Abrisqueta P, Scott D, Slack G, Steidl C, Mottok A, Gascoyne R, et al.
Ann Oncol . 2017 Sep; 28(10):2489-2495. PMID: 28961827
Background: Patients with mantle cell lymphoma (MCL) follow a heterogeneous clinical course. While they generally require treatment initiation shortly after diagnosis, it is unclear whether deferring treatment in selected patients...
2.
Muller E, Bauer S, Stuhmer T, Mottok A, Scholz C, Steinbrunn T, et al.
Leukemia . 2016 Oct; 31(4):922-933. PMID: 27686868
Direct therapeutic targeting of oncogenic RAS is currently still impossible due to lack of suitable pharmacological inhibitors. Because specific blockade of druggable RAS effectors might represent an alternative treatment approach,...
3.
Rohr J, Guo S, Huo J, Bouska A, Lachel C, Li Y, et al.
Leukemia . 2016 Jan; 30(5):1062-70. PMID: 26719098
Peripheral T-cell lymphomas (PTCLs) comprise a heterogeneous group of mature T-cell neoplasms with a poor prognosis. Recently, mutations in TET2 and other epigenetic modifiers as well as RHOA have been...
4.
Linz C, Muller-Richter U, Buck A, Mottok A, Ritter C, Schneider P, et al.
Int J Oral Maxillofac Surg . 2014 Dec; 44(1):8-15. PMID: 25442744
Detecting bone invasion in oral cancer is crucial for therapy planning and the prognosis. The present study evaluated cone beam computed tomography (CBCT) for detecting bone invasion in comparison to...
5.
Bommert K, Effenberger M, Leich E, Kuspert M, Murphy D, Langer C, et al.
Leukemia . 2012 Jul; 27(2):441-50. PMID: 22772059
Y-box binding protein 1 (YB-1) functions as a translational regulator and has been suggested to elevate MYC mRNA translation via an internal ribosome entry segment (IRES) point mutation in multiple...
6.
Ritter C, Wartenberg M, Mottok A, Steger U, Goltz J, Hahn D, et al.
Cardiovasc Intervent Radiol . 2011 Mar; 35(1):198-202. PMID: 21431968
Spontaneous rupture of hepatocellular carcinoma (HCC) after transcatheter arterial chemoembolization (TACE) is a rare and life-threatening complication. Pathophysiologic mechanisms are not yet fully known; it is suggested that rupture is...
7.
Reitter A, Fischer D, Buxmann H, Nitschke Y, Rutsch F, Mottok A, et al.
Fetal Diagn Ther . 2009 Jun; 25(2):264-8. PMID: 19521093
Prenatal diagnosis of generalized arterial calcification of infancy (GACI) (OMIM #208000) is difficult and rare. There are various known gene mutations in ENPP1 (ectonucleotide pyrophosphatase/phosphodiesterase 1) locus 6q22-q23. We present...
8.
Tedoldi S, Mottok A, Ying J, Paterson J, Cui Y, Facchetti F, et al.
J Pathol . 2007 Oct; 213(4):429-40. PMID: 17935142
The neoplastic Reed-Sternberg cells characteristic of classical Hodgkin's lymphoma (cHL) are of B-cell origin but they almost always show striking loss of a range of B-cell-associated molecules. In contrast, the...
9.
Mottok A, Hansmann M, Brauninger A
J Clin Pathol . 2005 Aug; 58(9):1002-4. PMID: 16126891
Background: The lymphocytic and histiocytic (L&H) cells of lymphocyte predominant Hodgkin lymphoma (HL) originate from germinal centre B cells and carry mutated V gene rearrangements, usually with intraclonal diversity. It...