A Mario Marcondes
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Explore the profile of A Mario Marcondes including associated specialties, affiliations and a list of published articles.
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Articles
17
Citations
349
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0
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Recent Articles
1.
Luo W, Gardenswartz A, Hoang H, Chu Y, Tian M, Liao Y, et al.
Mol Ther Oncol
. 2024 Nov;
32(4):200894.
PMID: 39554906
Pediatric patients with recurrent metastatic neuroblastoma (NB) have a dismal 5-year survival. Novel therapeutic approaches are urgently needed. The melanoma cell adhesion molecule (MCAM/CD146/MUC18) is expressed in a variety of...
2.
Srinagesh H, Jackson C, Shiraz P, Jeyakumar N, Hamilton M, Egeler E, et al.
Blood
. 2024 Jul;
144(16):1689-1698.
PMID: 38968138
Although chimeric antigen receptor (CAR) T-cell (CAR-T) therapy has revolutionized the treatment of B-cell malignancies, many patients relapse and therefore strategies to improve antitumor immunity are needed. We previously designed...
3.
Bhagat T, Chen S, Bartenstein M, Barlowe A, von Ahrens D, Choudhary G, et al.
Cancer Res
. 2017 Jul;
77(18):4846-4857.
PMID: 28684528
The bone marrow microenvironment influences malignant hematopoiesis, but how it promotes leukemogenesis has not been elucidated. In addition, the role of the bone marrow stroma in regulating clinical responses to...
4.
Marcondes A, Hockenbery D, Lesnikova M, Dinarello C, Woolfrey A, Gernsheimer T, et al.
Biol Blood Marrow Transplant
. 2016 May;
22(9):1596-1601.
PMID: 27223109
α1-Antitrypsin (AAT) is a serine protease inhibitor with anti-inflammatory, antiapoptotic, and immunomodulatory properties. It has therapeutic efficacy in animal models of autoimmune diseases, inflammatory disorders, and transplantation. In a phase...
5.
Karoopongse E, Marcondes A, Yeung C, Holman Z, Kowdley K, Campbell J, et al.
Biol Blood Marrow Transplant
. 2016 Apr;
22(7):1173-1181.
PMID: 27060441
Iron overload is common in patients undergoing hematopoietic cell transplantation (HCT). Peritransplant events, such as total body irradiation (TBI), and the effects of donor cell infusion may contribute to iron...
6.
Karoopongse E, Yeung C, Byon J, Ramakrishnan A, Holman Z, Jiang P, et al.
PLoS One
. 2014 Sep;
9(9):e107817.
PMID: 25225797
Both DNA and histone methylation are dysregulated in the myelodysplastic syndromes (MDS). Based on preliminary data we hypothesized that dysregulated interactions of KDM2B, let-7b and EZH2 signals lead to an...
7.
Marcondes A, Karoopongse E, Lesnikova M, Margineantu D, Welte T, Dinarello C, et al.
Blood
. 2014 Sep;
124(18):2881-91.
PMID: 25224412
Hematopoietic cell transplantation is curative in many patients. However, graft-versus-host disease (GVHD), triggered by alloreactive donor cells, has remained a major complication. Here, we show an inverse correlation between plasma...
8.
Li X, Xu F, Karoopongse E, Marcondes A, Lee K, Kowdley K, et al.
Biol Blood Marrow Transplant
. 2013 May;
19(8):1210-9.
PMID: 23707854
Hepatic iron overload is common in patients undergoing hematopoietic cell transplantation. We showed previously in a murine model that transplantation of allogeneic T cells induced iron deposition and down-regulation of...
9.
Patel N, Black J, Chen X, Marcondes A, Grady W, Lawlor E, et al.
Sarcoma
. 2012 Oct;
2012:498472.
PMID: 23024594
The role of aberrant DNA methylation in Ewing sarcoma is not completely understood. The methylation status of 503 genes in 52 formalin-fixed paraffin-embedded EWS tumors and 3 EWS cell lines...
10.
Li X, Xu F, Chang C, Byon J, Papayannopoulou T, Deeg H, et al.
Haematologica
. 2012 Sep;
98(3):414-9.
PMID: 22983574
The transcription factor TWIST-1 is up-regulated in CD34(+) cells in myelodysplastic syndrome and is involved in resistance to apoptosis. There is evidence that TWIST-1 affects apoptosis via microRNAs (miRs). Expression...