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A M Yuan

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Recent Articles
1.
Ksander G, Erion M, Yuan A, Diefenbacher C, Cote D, Levens N
J Med Chem . 1994 Jun; 37(12):1823-32. PMID: 8021921
A variety of compounds were prepared to determine whether dual angiotensin converting enzyme (ACE)/thromboxane synthase (TxS) inhibition could be obtained in the same molecule. These compounds would be used to...
2.
Ksander G, Diefenbacher C, Yuan A, Clark F, Sakane Y, Ghai R
J Med Chem . 1989 Dec; 32(12):2519-26. PMID: 2585440
The synthesis of two new series of dicarboxylic acid dipeptides and two sulfhydryl-containing inhibitors are described. The in vitro enkephalinase inhibition data and some in vivo analgesic data are presented...
3.
Ksander G, Yuan A, Diefenbacher C, Stanton J
J Med Chem . 1985 Nov; 28(11):1606-11. PMID: 2999395
The preparation of two series of N-carbobenzoxy-gamma-D-glutamyl secondary 2S amino acids and (N-substituted gamma-D-glutamyl)indoline-2(S)-carboxylic acid dipeptides is described. In vitro inhibition of angiotensin converting enzyme (ACE) is reported for each...
4.
GRUENFELD N, Stanton J, Yuan A, Ebetino F, BROWNE L, Gude C, et al.
J Med Chem . 1983 Sep; 26(9):1277-82. PMID: 6310113
The preparation of a series of 1-glutarylindoline-2(S)-carboxylic acid derivatives, 6a-v and 21a-c, is described. The above compounds were tested for inhibition of angiotensin converting enzyme. The structure-activity relationship of the...
5.
Stanton J, GRUENFELD N, Babiarz J, Ackerman M, FRIEDMANN R, Yuan A, et al.
J Med Chem . 1983 Sep; 26(9):1267-77. PMID: 6310112
The synthesis of N-(3-mercaptopropionyl)-N-arylglycines (14a-x),- N-arylalanines (15a,b),-N-cycloalkylglycines (16a-k), and -1,2,3,4-tetrahydroisoquinoline-3-carboxylic acids (17a-d), -1,2,3,4-tetrahydroquinoline-2-carboxylic acids (18a-f), and -indoline-2-carboxylic acids (19a-k) is described. In vitro inhibition of angiotensin converting enzyme (ACE) is...