A M Scherbakov
Overview
Explore the profile of A M Scherbakov including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
78
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Recent Articles
1.
Bogdanov F, Balakhonov R, Volkov E, Sonin I, Andreeva O, Sorokin D, et al.
Bioorg Chem
. 2024 Nov;
153:107942.
PMID: 39515131
The aim of this study was to develop a new series of isocryptolepines and evaluate their antiproliferative and antiestrogenic activities on cancer cells. A series of isocryptolepine derivatives were synthesized...
2.
Kuznetsov Y, Tserfas M, Scherbakov A, Andreeva O, Salnikova D, Bozhenko E, et al.
Steroids
. 2024 Nov;
212:109527.
PMID: 39486666
Starting from 3-methoxyestra-1,3,5(10),16-tetraene-17-carbaldehydes of natural (13β) and epimeric (13α) series, a series of isomeric 3-hydroxy-17-hydroxymethylestra-1,3,5(10)-trienes, including those containing 16α,17α-annulated cyclopropane and cyclohexane ring D', were prepared using the Corey-Chaykovsky and...
3.
Scherbakov A, Balakhonov R, Salnikova D, Sorokin D, Yadykov A, Markosyan A, et al.
Org Biomol Chem
. 2021 Sep;
19(35):7670-7677.
PMID: 34524348
A novel quinazoline series of photoswitchable combretastatin A-4 (CA-4) analogues were synthesized and their photochemical properties and antiproliferative activity against A431 epidermoid carcinoma cells were studied. It was found that...
4.
Yastrebova M, Khamidullina A, Tatarskiy V, Scherbakov A
Acta Naturae
. 2021 May;
13(1):76-90.
PMID: 33959388
The review analyzes Snail family proteins, which are transcription factors involved in the regulation of the epithelial-mesenchymal transition (EMT) of tumor cells. We describe the structure of these proteins, their...
5.
Scherbakov A, Shestakova E, Galeeva K, Bogush T
Mol Biol (Mosk)
. 2019 Jun;
53(3):502-512.
PMID: 31184616
BRCA1 (breast cancer 1) protein is involved in the genome stability maintenance participating in homologous recombination-dependent DNA repair. Disruption of BRCA1 functioning is associated with breast and ovarian cancer. Despite...
6.
Semina S, Scherbakov A, Kovalev S, Shevchenko V, Krasilnikov M
Cancer Invest
. 2017 Sep;
35(8):506-518.
PMID: 28910558
Using estrogen-dependent MCF-7 breast cancer cells and tamoxifen-resistant MCF-7/T subline we have shown that their co-cultivation lead to increase in tamoxifen resistance in the parent MCF-7 cells. The proteome analysis...
7.
Scherbakov A, Levina I, Kulikova L, Fedyushkina I, Skvortsov V, Veselovsky A, et al.
Biomed Khim
. 2016 Jul;
62(3):290-4.
PMID: 27420621
The cytotoxic activity of synthetic progestins (pregna-D'-pentaranes) II-V full agonists of the progesterone receptor (PR) for PR-positive and PR-negative cells of human breast carcinoma was studied. These compounds were more...
8.
Scherbakov A, Gershtein E, Korotkova E, Ovchinnikova L, Ovsii O, Ermilova V, et al.
Bull Exp Biol Med
. 2016 May;
160(6):802-6.
PMID: 27165081
Immunohistochemical method was used to assay for Snail family regulatory proteins of epithelial-mesenchymal transition, their NF-κB coactivator, and the components of VEGF signaling pathway (VEGF and its receptors VEGFR1 and...
9.
Sorokin D, Scherbakov A, Yakushina I, Semina S, Gudkova M, Krasilnikov M
Bull Exp Biol Med
. 2016 Feb;
160(4):555-9.
PMID: 26902354
We studied the mechanisms of adaptation of human breast cancer cells MCF-7 to hypoxia and analyzed the role of AMPK/mTOR signaling pathway in the maintenance of cell proliferation under hypoxic...
10.
Scherbakov A, Andreeva O
Acta Naturae
. 2015 Oct;
7(3):133-9.
PMID: 26483970
Phytoestrogens are a group of plant-derived compounds with an estrogen-like activity. In mammalians, phytoestrogens bind to the estrogen receptor (ER) and participate in the regulation of cell growth and gene...