A M Middleton
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Explore the profile of A M Middleton including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
184
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Recent Articles
1.
Brown L, Middleton A, King J, Loose M
Bull Math Biol
. 2016 Mar;
78(3):436-67.
PMID: 26934886
The earliest cell fate decisions in a developing embryo are those associated with establishing the germ layers. The specification of the mesoderm and endoderm is of particular interest as the...
2.
Pratten J, Wiecek J, Mordan N, Lomax A, Patel N, Spratt D, et al.
Int J Dent Hyg
. 2015 Jul;
14(3):209-14.
PMID: 26198308
Objectives: Sodium bicarbonate has been shown clinically to be efficacious at removing dental plaque; however, its effect of mechanism against biofilms has not been evaluated in vitro. Here, we used...
3.
Middleton A, King J, Loose M
J Math Biol
. 2012 Oct;
67(6-7):1393-424.
PMID: 23070212
Nodal signals are key regulators of mesoderm and endoderm development in vertebrate embryos. It has been observed experimentally that in Xenopus embryos the spatial range of Nodal signals is restricted...
4.
Middleton A, King J, Bennett M, Owen M
Bull Math Biol
. 2010 Feb;
72(6):1383-407.
PMID: 20135237
The hormone auxin is implicated in regulating a diverse range of developmental processes in plants. Auxin acts in part by inducing the Aux/IAA genes. The associated pathway comprises multiple negative...
5.
Middleton A, King J, Loose M
J Theor Biol
. 2009 Jun;
260(1):41-55.
PMID: 19490918
In this paper we develop a model of mesendoderm specification in Xenopus laevis based on an existing gene regulation network. The mesendoderm is a population of cells that may contribute...
6.
Charman K, Fernandez P, Loewy Z, Middleton A
Lett Appl Microbiol
. 2009 Feb;
48(4):472-7.
PMID: 19228292
Aim: To determine the effect of the surface roughness of denture acrylic on the attachment of Streptococcus oralis. Methods And Results: Roughened denture acrylic samples were assessed for bacterial attachment,...
7.
Gammon K, Livens S, Pawlowsky K, Rawling S, Chandra S, Middleton A
Lett Appl Microbiol
. 2007 Feb;
44(3):262-7.
PMID: 17309502
Aims: To develop a rapid real-time polymerase chain reaction (PCR) method to detect Gluconobacter and Gluconacetobacter species in electrolyte replacement drinks. Methods And Results: Samples of electrolyte replacement drinks were...
8.
Middleton A, Chadwick M, Nicholson A, Dewar A, Groger R, Brown E, et al.
Respir Med
. 2004 Dec;
98(12):1203-6.
PMID: 15588041
Mycobacterium species adhere to the respiratory mucosa via mucus and fibronectin of extracellular matrix exposed by damaged epithelium. We have investigated whether inhibiting adherence to fibronectin influences subsequent infection of...
9.
Middleton A, Chadwick M, Nicholson A, Wilson R, Thornton D, Kirkham S, et al.
Exp Lung Res
. 2004 Feb;
30(1):17-29.
PMID: 14967601
Mycobacteria adhere specifically to extracellular matrix (ECM) and mucus with a fibrous, but not globular, appearance, in organ cultures of human respiratory mucosa examined by scanning electron microscopy. Previously, light...
10.
Middleton A, Dowling R, Mitchell J, Watanabe S, Rutman A, Pritchard K, et al.
Respir Med
. 2003 Apr;
97(4):375-81.
PMID: 12693797
The pathogenicity of Haemophilus parainfluenzae (Hpi) in the respiratory tract is unclear, in contrast to the accepted pathogenicity of its close relative non-typable H. influenzae. We have investigated the interaction...