A M Heacock
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Explore the profile of A M Heacock including associated specialties, affiliations and a list of published articles.
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35
Citations
216
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Recent Articles
1.
Agranoff B, Feldman E, Heacock A, Schwartz M
Neurochem Int
. 2010 May;
1C:487-500.
PMID: 20487757
The visual system of primitive vertebrates has long served as a useful model for the resynthesis of damaged neurons. The prior optic nerve crush imparts a marked tendency on the...
2.
Dybowski J, Heacock A, Agranoff B
Brain Res
. 1999 Oct;
842(1):62-72.
PMID: 10526096
The effects of intraocular (i.o.) administration of the alkaloid colchicine on visual recovery following axotomy of the goldfish optic nerve were investigated. Under the experimental conditions used, control goldfish recovered...
3.
Sorensen S, Linseman D, McEwen E, Heacock A, Fisher S
J Pharmacol Exp Ther
. 1999 Jul;
290(2):603-10.
PMID: 10411568
Recent evidence supporting a role for phosphoinositides in the endocytosis of phospholipase C-coupled receptors has prompted an investigation of whether there exists a similar requirement for the internalization of adenylyl...
4.
Sorensen S, Linseman D, McEwen E, Heacock A, Fisher S
Mol Pharmacol
. 1998 Jun;
53(5):827-36.
PMID: 9584208
A role for phosphoinositides in the endocytosis of muscarinic cholinergic receptors (mAChRs) has been investigated via inhibition of the activity of phosphatidylinositol-4-kinase (PI4K). Pretreatment of SH-SY5Y neuroblastoma cells with micromolar...
5.
Heacock A, Agranoff B
Biochim Biophys Acta
. 1997 Nov;
1348(1-2):166-72.
PMID: 9370329
CDP-diacylglycerol resides at the branch point of glycerolipid biosynthesis as precursor of both the phosphoinositides and phosphatidylglycerol. The discovery of the phosphoinositide signal transduction pathway and the recognition of its...
6.
Heacock A, Agranoff B
Neurochem Res
. 1997 Oct;
22(10):1179-85.
PMID: 9342720
A role for protein phosphorylation in the process of neurite outgrowth has been inferred from many studies of the effects of protein kinase inhibitors and activators on cultured neurotumor cells...
7.
Heacock A, Uhler M, Agranoff B
J Neurochem
. 1996 Nov;
67(5):2200-3.
PMID: 8863531
A critical step in the supply of substrate for the phosphoinositide signal transduction pathway is the formation of the liponucleotide intermediate, CDP-diacylglycerol, catalyzed by CDP-diacylglycerol synthase. Further insight into the...
8.
Heacock A, Seguin E, Agranoff B
J Neurochem
. 1993 Mar;
60(3):1087-92.
PMID: 8382261
Two methods for the measurement of receptor-activated phosphoinositide turnover were evaluated for their degree of correspondence in slices of rat brain; they involved the Li(+)-dependent accumulations of either [3H]-inositol-labeled inositol...
9.
Fisher S, Heacock A, Agranoff B
J Neurochem
. 1992 Jan;
58(1):18-38.
PMID: 1309233
No abstract available.
10.
Fisher S, Heacock A, Seguin E, Agranoff B
Mol Pharmacol
. 1990 Jul;
38(1):54-63.
PMID: 2164631
The contribution of polyphosphoinositides to muscarinic receptor-stimulated phosphoinositide turnover has been evaluated for intact and digitonin-permeabilized human SK-N-SH neuroblastoma cells. Addition of carbamoylcholine to [3H]inositol-prelabeled intact cells resulted in a...