A L Sharpley
Overview
Explore the profile of A L Sharpley including associated specialties, affiliations and a list of published articles.
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32
Citations
530
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Recent Articles
1.
Cooper C, Godlewska B, Sharpley A, Barnes E, Cowen P, Harmer C
Psychol Med
. 2017 Sep;
48(6):998-1007.
PMID: 28889805
Background: Treatment of medical patients with the inflammatory cytokine, interferon-α (IFN-α), is frequently associated with the development of clinical depressive symptomatology. Several important biological correlates of the effect of IFN-α...
2.
Sharpley A, Attenburrow M, Cowen P
Int J Psychiatry Clin Pract
. 2014 Jun;
1(2):107-17.
PMID: 24936665
Insomnia is a subjective term describing the perception of disturbed or inadequate sleep. Causes include medical diseases, psychiatric disorders, drugs, behavioural factors, circadian dysrhythmias and primary sleep disorders. Insomnia is...
3.
Williams R, Sharpley A, Cowen P
J Psychopharmacol
. 2012 Feb;
8(3):168-70.
PMID: 22298584
We studied the effect of repeated treatment with selective serotonin re-uptake inhibitors (SSRIs) on the sensitivity of brain 5-HT(2C) receptors, by measuring the decrease in slow wave sleep (SWS) that...
4.
Solomon R, Sharpley A, Cowen P
J Psychopharmacol
. 2012 Jan;
3(3):125-9.
PMID: 22282895
The effect on slow wave sleep (SWS) of 5-HT antagonists with different affinities for 5-HT(1) and 5-HT(2) receptors was investigated using ambulatory EEG monitoring in normal volunteers. The selective 5-HT(...
5.
Wilson S, Nutt D, Alford C, Argyropoulos S, Baldwin D, Bateson A, et al.
J Psychopharmacol
. 2010 Sep;
24(11):1577-601.
PMID: 20813762
Sleep disorders are common in the general population and even more so in clinical practice, yet are relatively poorly understood by doctors and other health care practitioners. These British Association...
6.
Murray B, Cowen P, Sharpley A
Pharmacopsychiatry
. 2001 Aug;
34(4):155-7.
PMID: 11518478
Ginkgo biloba extracts (GBE) have been shown to be as effective as anti-cholinesterase inhibitors in improving the cognitive test scores of patients with dementia. Although it has been assumed that...
7.
Vassallo C, Feldman E, Peto T, Castell L, Sharpley A, Cowen P
Psychol Med
. 2001 May;
31(4):585-91.
PMID: 11352361
Background: Chronic fatigue syndrome (CFS) has been associated with increased prolactin (PRL) responses to the serotonin (5-HT) releasing agent fenfluramine. It is not known whether this abnormality is due to...
8.
Sharpley A, Vassallo C, Pooley E, Harrison P, Cowen P
Psychopharmacology (Berl)
. 2001 Feb;
153(2):271-2.
PMID: 11205431
No abstract available.
9.
Brunello N, Armitage R, Feinberg I, Holsboer-Trachsler E, Leger D, Linkowski P, et al.
Neuropsychobiology
. 2000 Oct;
42(3):107-19.
PMID: 11015028
A wide range of studies have been published over the past two decades that involve the intersection of sleep EEG, insomnia, psychiatric illness (especially depressive disorders) and psychopharmacology. Much of...
10.
Sharpley A, Vassallo C, Cowen P
Biol Psychiatry
. 2000 Mar;
47(5):468-70.
PMID: 10704958
Background: The study aimed to determine the effects of the atypical antipsychotic agent, olanzapine, on the polysomnogram in healthy subjects. We predicted that olanzapine, via serotonin(2C) (5-HT(2C)) receptor blockade, would...