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A L Rothermel

Explore the profile of A L Rothermel including associated specialties, affiliations and a list of published articles. Areas
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Articles 15
Citations 453
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Recent Articles
1.
Xu D, Alegre M, Varga S, Rothermel A, Collins A, Pulito V, et al.
Cell Immunol . 2000 Mar; 200(1):16-26. PMID: 10716879
Orthoclone OKT 3 (mOKT3) is a highly effective agent for the reversal of steroid-resistant renal allograft rejection. However, its wider use has been limited by the development of a human...
2.
OConnor D, Schechner J, Adida C, Mesri M, Rothermel A, Li F, et al.
Am J Pathol . 2000 Feb; 156(2):393-8. PMID: 10666367
Mechanisms controlling endothelial cell survival during angiogenesis were investigated. Stimulation of quiescent endothelial cells with mitogens, including vascular endothelial growth factor and basic fibroblast growth factor, induced up to approximately...
3.
Li F, Ackermann E, Bennett C, Rothermel A, Plescia J, Tognin S, et al.
Nat Cell Biol . 1999 Dec; 1(8):461-6. PMID: 10587640
Here we investigate the role of the control of apoptosis in normal cell division. We show that interference with the expression or function of the apoptosis inhibitor survivin causes caspase-dependent...
4.
Rothermel A, Altieri D
Proc Natl Acad Sci U S A . 1998 May; 95(7):3816-20. PMID: 9520450
The antigen recognition of a profoundly immunosuppressive mAb, mAb 2E1, in vivo was investigated. In addition to the 62-kDa effector cell protease receptor 1, mAb 2E1 bound the 32-kDa T...
5.
Pulito V, Roberts V, Adair J, Rothermel A, Collins A, Varga S, et al.
J Immunol . 1996 Apr; 156(8):2840-50. PMID: 8609403
OKT4A, a murine mAb that recognizes an epitope on the CD4 receptor, is a potent immunosuppressive agent in vitro and in a variety of nonhuman primate models of graft rejection...
6.
Duchosal M, Rothermel A, McCONAHEY P, Dixon F, Altieri D
Nature . 1996 Mar; 380(6572):352-6. PMID: 8598931
Membrane receptors for blood proteases govern the clotting and fibrinolytic cascades, regulate signal transduction and control the growth of mesenchymal cells. Despite their importance in the development of vascular injury,...
7.
Adair J, Athwal D, Bodmer M, Bright S, Collins A, Pulito V, et al.
Hum Antibodies Hybridomas . 1994 Jan; 5(1-2):41-7. PMID: 7858182
OKT3 is a murine monoclonal antibody which recognizes an epitope on the epsilon-subunit within the human CD3 complex. OKT3 possesses potent immunosuppressive properties in vivo and has been proven effective...
8.
Gilbert K, Rothermel A, Ernst D, Hobbs M, Weigle W
Cell Immunol . 1992 Jun; 142(1):1-15. PMID: 1586950
Tolerant and nontolerant murine Th1 and Th2 clones, specific for human gamma-globulin (HGG), were compared for their ability to promote cell cycle entry and progression by B cells in vitro....
9.
Hobbs M, Ernst D, Torbett B, Glasebrook A, Rehse M, McQuitty D, et al.
J Cell Biochem . 1991 Aug; 46(4):312-20. PMID: 1684583
Splenocytes from young adult or old C57BL/6NNia mice were stimulated in vitro with the anti-CD3 epsilon mAb, 145-2C11, in either soluble (2C11s) or plate-bound (2C11i) form. In the young group,...
10.
Rothermel A, Gilbert K, Weigle W
Cell Immunol . 1991 Jun; 135(1):1-15. PMID: 1708308
Human gamma globulin-specific T helper cell (Th) clones, activated by HGG in the presence of antigen (Ag)-presenting cells, stimulated polyclonal B cell proliferation. Both Th1 and Th2 clones induced B...