A L MacKay
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Explore the profile of A L MacKay including associated specialties, affiliations and a list of published articles.
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45
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1444
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Recent Articles
1.
Wiggermann V, Vavasour I, Kolind S, MacKay A, Helms G, Rauscher A
NMR Biomed
. 2020 Mar;
33(12):e4277.
PMID: 32124505
Multi-compartment T mapping has gained particular relevance for the study of myelin water in the brain. As a facilitator of rapid saltatory axonal signal transmission, myelin is a cornerstone indicator...
2.
Neva J, Lakhani B, Brown K, Wadden K, Mang C, Ledwell N, et al.
Behav Brain Res
. 2015 Oct;
297:187-95.
PMID: 26467603
In individuals with multiple sclerosis (MS), transcranial magnetic stimulation (TMS) may be employed to assess the integrity of corticospinal system and provides a potential surrogate biomarker of disability. The purpose...
3.
Barta R, Kalantari S, Laule C, Vavasour I, MacKay A, Michal C
J Magn Reson
. 2015 Aug;
259:56-67.
PMID: 26295169
The fundamental basis of T1 and T2 contrast in brain MRI is not well understood; recent literature contains conflicting views on the nature of relaxation in white matter (WM). We...
4.
Borich M, MacKay A, Vavasour I, Rauscher A, Boyd L
Neuroimage Clin
. 2013 Nov;
2:569-80.
PMID: 24179808
Multi-component T2 relaxation imaging (MCRI) provides specific in vivo measurement of myelin water content and tissue water environments through myelin water fraction (MWF), intra/extra-cellular water fraction (I/EWF) and intra/extracellular and...
5.
Sturrock A, Laule C, Decolongon J, Dar Santos R, Coleman A, Creighton S, et al.
Neurology
. 2010 Nov;
75(19):1702-10.
PMID: 21060093
Objectives: To evaluate in vivo brain metabolite differences in control subjects, individuals with premanifest Huntington disease (pre-HD), and individuals with early HD using ¹H magnetic resonance spectroscopy (MRS) and to...
6.
Brief E, Vavasour I, Laule C, Li D, MacKay A
NMR Biomed
. 2010 Oct;
23(9):1033-7.
PMID: 20963799
The T(1) values of metabolites were measured in eight subjects with clinically definite multiple sclerosis (MS) having at least one large brain lesion (2.6 ± 0.7 mL) and in eight...
7.
Laule C, Vavasour I, Zhao Y, Traboulsee A, Oger J, Vavasour J, et al.
Mult Scler
. 2010 Jun;
16(6):670-7.
PMID: 20558500
Background: Spinal cord involvement in multiple sclerosis (MS) is common and an important element in disability. Previous studies demonstrated smaller cervical cord area at the C2 level in MS compared...
8.
Brief E, Moll R, Li D, MacKay A
NMR Biomed
. 2008 Dec;
22(3):349-54.
PMID: 19107764
Magnetic resonance spectroscopy (MRS) has been coupled with a multi-echo imaging sequence to determine the relaxation corrected signal areas of the metabolites and the tissue water. Stimulated echo acquisition mode...
9.
MacKay A, Vavasour I, Rauscher A, Kolind S, Madler B, Moore G, et al.
Neuroimaging Clin N Am
. 2008 Dec;
19(1):1-26.
PMID: 19064196
This article provides an overview of relaxation times and their application to normal brain and brain and cord affected by multiple sclerosis. The goal is to provide readers with an...
10.
Vavasour I, Laule C, Li D, Oger J, Moore G, Traboulsee A, et al.
J Neurol Sci
. 2008 Sep;
276(1-2):49-53.
PMID: 18822435
Multiple sclerosis (MS) is characterised by focal areas that undergo cycles of demyelination and remyelination. Although conventional magnetic resonance imaging is very effective in localising areas of damage, these techniques...