A L Gartel
Overview
Explore the profile of A L Gartel including associated specialties, affiliations and a list of published articles.
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Articles
27
Citations
717
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Recent Articles
1.
Khan I, Kaempf A, Raghuwanshi S, Chesnokov M, Zhang X, Wang Z, et al.
Blood Cancer J
. 2023 Aug;
13(1):128.
PMID: 37607920
No abstract available.
2.
Khan I, Halasi M, Zia M, Gann P, Gaitonde S, Mahmud N, et al.
Leukemia
. 2016 Oct;
31(1):251-255.
PMID: 27694928
No abstract available.
3.
4.
Radhakrishnan S, Halasi M, Bhat U, Kurmasheva R, Houghton P, Gartel A
Oncogene
. 2007 Aug;
27(5):694-9.
PMID: 17724478
We have previously described the identification of a nucleoside analog transcriptional inhibitor ARC (4-amino-6-hydrazino-7-beta-D-ribofuranosyl-7H-pyrrolo[2,3-d]-pyrimidine-5-carboxamide) that was able to induce apoptosis in cancer cell lines of different origin. Here, we report...
5.
Radhakrishnan S, Bhat U, Halasi M, Gartel A
Oncogene
. 2007 Aug;
27(9):1306-9.
PMID: 17724473
Tumor suppressor p53 is stabilized in response to gamma-irradiation or treatment with DNA-damaging agents, and as a result p53 transcriptionally activates its targets leading to cell-cycle arrest or apoptosis. P-TEFb...
6.
Nekhai S, Bhat U, Ammosova T, Radhakrishnan S, Jerebtsova M, Niu X, et al.
Oncogene
. 2006 Dec;
26(26):3899-903.
PMID: 17173067
Human immunodeficiency virus (HIV) and hepatitis C virus (HCV) pose major public health concerns worldwide. HCV is clearly associated with the occurrence of hepatocellular carcinoma, and recently HIV infection has...
7.
Radhakrishnan S, Gierut J, Gartel A
Oncogene
. 2005 Nov;
25(12):1812-5.
PMID: 16261158
The p53 tumor-suppressor is a transcription factor that is stabilized in response to cellular stress leading to growth arrest or apoptosis. p21(WAF1/CIP1) is a major transcriptional target of p53 and...
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9.
Gartel A, Ye X, Goufman E, Shianov P, Hay N, Najmabadi F, et al.
Proc Natl Acad Sci U S A
. 2001 Mar;
98(8):4510-5.
PMID: 11274368
The cyclin-dependent kinase inhibitor p21((WAF1/CIP1)) inhibits proliferation both in vitro and in vivo, and overexpression of p21 in normal and tumor cell lines results in cell cycle arrest. In contrast,...
10.
Sp1 and Sp3 activate p21 (WAF1/CIP1) gene transcription in the Caco-2 colon adenocarcinoma cell line
Gartel A, Goufman E, Najmabadi F, Tyner A
Oncogene
. 2000 Nov;
19(45):5182-8.
PMID: 11064455
The CDK inhibitor p21WAF1/CIP1 is a negative regulator of the cell cycle, and its expression is induced during terminal differentiation in vitro and in vivo. Expression of p21 is controlled...