A L Bartels
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Explore the profile of A L Bartels including associated specialties, affiliations and a list of published articles.
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11
Citations
750
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Recent Articles
1.
Timmers E, Kuiper A, Smit M, Bartels A, Kamphuis D, Wolf N, et al.
Parkinsonism Relat Disord
. 2017 Oct;
45:57-62.
PMID: 29066160
Background: In patients with GTP-cyclohydrolase deficient dopa-responsive dystonia (DRD) the occurrence of associated non-motor symptoms (NMS) is to be expected. Earlier studies report conflicting results with regard to the nature...
2.
Smit M, Kuiper A, Han V, Jiawan V, Douma G, Van Harten B, et al.
Parkinsonism Relat Disord
. 2016 Jun;
30:7-12.
PMID: 27321988
Introduction: The aim of this study was to systematically investigate the prevalence of psychiatric disorders and factors influencing health-related quality of life (HR-QoL) in cervical dystonia (CD) patients, in the...
3.
Smit M, Bartels A, van Faassen M, Kuiper A, Niezen-Koning K, Kema I, et al.
Neurosci Biobehav Rev
. 2016 Apr;
65:264-75.
PMID: 27073048
Dystonia is a hyperkinetic movement disorder characterized by sustained or intermittent muscle contractions. Emerging data describe high prevalences of non-motor symptoms, including psychiatric co-morbidity, as part of the phenotype of...
4.
Bartels A
Curr Pharm Des
. 2011 Aug;
17(26):2771-7.
PMID: 21831040
Protection of the brain is strengthened by active transport and ABC transporters. P-glycoprotein (P-gp) at the blood-brain barrier (BBB) functions as an active efflux pump by extruding a substrate from...
5.
Bartels A, de Klerk O, Kortekaas R, de Vries J, Leenders K
Curr Top Med Chem
. 2010 Jul;
10(17):1775-84.
PMID: 20645917
P-glycoprotein (P-gp) at the blood-brain barrier (BBB) functions as an active efflux pump by extruding a wide range of substrates from the brain. This is important for maintaining loco-regional homeostasis...
6.
Bartels A, Willemsen A, Doorduin J, de Vries E, Dierckx R, Leenders K
Parkinsonism Relat Disord
. 2009 Jun;
16(1):57-9.
PMID: 19487152
Unlabelled: [(11)C]-PK11195 PET has been used for in vivo brain imaging of microglia activation in Parkinson's disease (PD) patients. COX-2 inhibition has been shown to reduce neuroinflammation and neurodegeneration in...
7.
Bartels A, van Berckel B, Lubberink M, Luurtsema G, Lammertsma A, Leenders K
Parkinsonism Relat Disord
. 2008 Mar;
14(6):505-8.
PMID: 18325822
The cause of Parkinson's disease (PD) is unknown. Genetic susceptibility and exposure to environmental toxins contribute to specific neuronal loss in PD. Decreased blood-brain barrier (BBB) P-glycoprotein (P-gp) efflux function...
8.
Bartels A, Willemsen A, Kortekaas R, de Jong B, de Vries R, de Klerk O, et al.
J Neural Transm (Vienna)
. 2008 Feb;
115(7):1001-9.
PMID: 18265929
Decreased blood-brain barrier (BBB) efflux function of the P-glycoprotein (P-gp) transport system could facilitate the accumulation of toxic compounds in the brain, increasing the risk of neurodegenerative pathology such as...
9.
Bartels A, Balash Y, Gurevich T, Schaafsma J, Hausdorff J, Giladi N
J Clin Neurosci
. 2003 Sep;
10(5):584-8.
PMID: 12948464
Background: The pathophysiology of freezing of gait (FOG) is unclear. Objective: To assess the relationships between FOG and other parkinsonian features in Parkinson's disease (PD), focusing on levodopa effects. Methods:...
10.
Schaafsma J, Balash Y, Gurevich T, Bartels A, Hausdorff J, Giladi N
Eur J Neurol
. 2003 Jun;
10(4):391-8.
PMID: 12823491
To assess the effect of levodopa on distinct freezing of gait (FOG) subtypes in patients with 'off' FOG. Nineteen patients (12 men, mean age 62.0 +/- 8.4 years) with Parkinson's...