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A Kanatsuka

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Articles 82
Citations 373
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Recent Articles
1.
Horie A, Tokuyama Y, Ishizuka T, Suzuki Y, Marumo K, Oshikiri K, et al.
Horm Metab Res . 2014 Jul; 46(11):814-8. PMID: 24977657
The aim of the present study was to determine whether the dipeptidyl peptidase (DPP)-4 inhibitor could repair pancreatic β-cell dysfunction and insulin resistance. Ten subjects with type 2 diabetes who...
2.
Kobayashi K, Yokoh H, Sato Y, Takemoto M, Uchida D, Kanatsuka A, et al.
Diabetes Obes Metab . 2014 Jan; 16(8):761-5. PMID: 24447683
We assessed the efficacy and safety of sitagliptin compared with α-glucosidase inhibitor (αGI) in 120 of Japanese patients with type 2 diabetes mellitus (T2DM) inadequately controlled on stable ≤2 mg/day...
3.
Murase Y, Imagawa A, Hanafusa T, Iwahashi H, Uchigata Y, Kanatsuka A, et al.
Diabetologia . 2007 Jan; 50(3):531-7. PMID: 17235525
Aims/hypothesis: The aim of the present study was to assess the development of microangiopathy in patients with fulminant type 1 diabetes, a novel subtype of type 1B diabetes. Materials And...
4.
Shimizu I, Makino H, Imagawa A, Iwahashi H, Uchigata Y, Kanatsuka A, et al.
J Clin Endocrinol Metab . 2005 Nov; 91(2):471-6. PMID: 16278271
Objective: The objective of this study was to characterize the clinical and immunogenetic features of Japanese pregnancy-associated fulminant type 1 diabetes (PF). A group of patients with PF was compared...
5.
Imagawa A, Hanafusa T, Uchigata Y, Kanatsuka A, Kawasaki E, Kobayashi T, et al.
Diabetologia . 2005 Feb; 48(2):294-300. PMID: 15688210
Aims/hypothesis: Fulminant type 1 diabetes, which is characterised by a markedly acute onset of diabetes and an absence of islet-related autoantibodies, accounts for 20% of type 1 diabetes in Japan....
6.
Tokuyama Y, Nozaki O, Kanatsuka A
Diabetes Res Clin Pract . 2001 Nov; 54(3):209-12. PMID: 11689276
Severe resistance to subcutaneous insulin but sensitivity to intravenous insulin persisted for 11 years in a 23-year-old diabetic woman. Several therapeutic trials revealed that (1) intravenous regular insulin improved her...
7.
Sano R, Miki T, Suzuki Y, Shimada F, Taira M, Kanatsuka A, et al.
Diabetes Res Clin Pract . 2001 Oct; 54(2):79-88. PMID: 11640991
We screened for mutations in the gene of insulin-sensitive phosphodiesterase 3B (PDE3B), which regulates antilipolytic actions of insulin via reduction of intracellular cyclic AMP levels, in Japanese patients with type...
8.
Tokuyama Y, Sakurai K, Yagui K, Hashimoto N, Saito Y, Kanatsuka A
Metabolism . 2001 Jul; 50(7):812-8. PMID: 11436187
We tried to characterize the clinical features associated with glucose metabolism in the development of diabetes. Study subjects were glucose-tolerant subjects without a family history of diabetes (normal glucose tolerance...
9.
Sakurai K, Seki N, Fujii R, Yagui K, Tokuyama Y, Shimada F, et al.
Horm Metab Res . 2000 Sep; 32(8):316-20. PMID: 10983627
Mutations of the hepatocyte nuclear factor 4 alpha (HNF-4alpha) gene have been demonstrated in maturity-onset diabetes of the young (MODY) 1 families. To investigate the possibility that the HNF-4alpha gene...
10.
Ishizuka N, Yagui K, Tokuyama Y, Yamada K, Suzuki Y, Miyazaki J, et al.
Metabolism . 1999 Dec; 48(12):1485-92. PMID: 10599977
Cytokines induce apoptosis in pancreatic beta cells, but the exact mechanisms and sequence of events are not clear. Here, we investigate a role for tumor necrosis factor alpha (TNF-alpha) in...