A K McClendon
Overview
Explore the profile of A K McClendon including associated specialties, affiliations and a list of published articles.
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Snapshot
Snapshot
Articles
6
Citations
326
Followers
0
Related Specialties
Related Specialties
Top 10 Co-Authors
Top 10 Co-Authors
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Published In
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Recent Articles
1.
Braden W, McClendon A, Knudsen E
Oncogene
. 2023 Mar;
42(16):1332.
PMID: 36949240
No abstract available.
2.
Comstock C, Augello M, Goodwin J, de Leeuw R, Schiewer M, Ostrander Jr W, et al.
Oncogene
. 2013 May;
32(48):5481-91.
PMID: 23708653
The cyclin/cyclin-dependent kinase (CDK)/retinoblastoma (RB)-axis is a critical modulator of cell cycle entry and is aberrant in many human cancers. New nodes of therapeutic intervention are needed that can delay...
3.
Dean J, Thangavel C, McClendon A, Reed C, Knudsen E
Oncogene
. 2010 May;
29(28):4018-32.
PMID: 20473330
A hallmark of cancer is the deregulation of cell-cycle machinery, ultimately facilitating aberrant proliferation that fuels tumorigenesis and disease progression. Particularly, in breast cancers, cyclin D1 has a crucial role...
4.
Reed C, Mayhew C, McClendon A, Yang X, Witkiewicz A, Knudsen E
Oncogene
. 2009 Oct;
28(50):4434-43.
PMID: 19838213
Hepatocellular carcinoma (HCC) is a significant worldwide health concern that is associated with discrete etiological events, encompassing viral infection, metabolic stress and genotoxic compounds. In particular, exposure to the genotoxic...
5.
Dean J, McClendon A, Stengel K, Knudsen E
Oncogene
. 2009 Oct;
29(1):68-80.
PMID: 19802012
The retinoblastoma tumor suppressor, RB, is a key regulator of cellular proliferation that is functionally inactivated at high frequency in human cancer. Although RB has been extensively studied with regard...
6.
Braden W, McClendon A, Knudsen E
Oncogene
. 2008 Sep;
27(56):7083-93.
PMID: 18776921
Cyclin-dependent kinases (CDKs) are important in regulating cell cycle transitions, particularly in coordinating DNA replication. Although the role of CDK2 activity on the replication apparatus has been extensively studied, the...