A John Ashcroft
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Explore the profile of A John Ashcroft including associated specialties, affiliations and a list of published articles.
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Articles
18
Citations
683
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Recent Articles
11.
Hill Q, Kelly R, Patalappa C, Whittle A, Scally A, Hughes A, et al.
Leuk Lymphoma
. 2011 Aug;
53(2):282-8.
PMID: 21846185
Improved survival in patients with hematological malignancy (HM) admitted to the intensive care unit (ICU) has largely been reported in uncontrolled cohorts from single academic institutions. We compared hospital mortality...
12.
Morgan G, Child J, Gregory W, Szubert A, Cocks K, Bell S, et al.
Lancet Oncol
. 2011 Jul;
12(8):743-52.
PMID: 21771568
Background: Bisphosphonates are the standard of care for reducing the risk of skeletal-related events in patients with bone lesions from multiple myeloma. The MRC Myeloma IX study was designed to...
13.
Morgan G, Davies F, Gregory W, Cocks K, Bell S, Szubert A, et al.
Lancet
. 2010 Dec;
376(9757):1989-99.
PMID: 21131037
Background: Bisphosphonates reduce the risk of skeletal events in patients with malignant bone disease, and zoledronic acid has shown potential anticancer effects in preclinical and clinical studies. We aimed to...
14.
Varghese A, Rawstron A, Ashcroft A, Moreton P, Owen R
Clin Lymphoma Myeloma
. 2009 Apr;
9(1):53-5.
PMID: 19362973
In this study we used bone marrow flow cytometry and immunohistochemistry to evaluate response to fludarabine therapy in patients with Waldenström's macroglobulinemia (WM)/lymphoplasmacytic lymphoma. Responses in serum M protein were...
15.
Davies F, Dring A, Li C, Rawstron A, Shammas M, OConnor S, et al.
Blood
. 2003 Aug;
102(13):4504-11.
PMID: 12947006
To define specific pathways important in the multistep transformation process of normal plasma cells (PCs) to monoclonal gammopathy of uncertain significance (MGUS) and multiple myeloma (MM), we have applied microarray...
16.
Dasgupta R, Adamson P, Davies F, Rollinson S, Roddam P, Ashcroft A, et al.
Blood
. 2003 Jun;
102(7):2345-50.
PMID: 12791655
Glutathione S-transferase P1 (GSTP1) is a phase 2 drug metabolism enzyme involved in the metabolism and detoxification of a range of chemotherapeutic agents. A single nucleotide polymorphism (Ile105Val) results in...
17.
Fenton J, Pratt G, Rawstron A, Sibley K, Rothwell D, Yates Z, et al.
Oncogene
. 2003 Feb;
22(7):1103-13.
PMID: 12592397
Using FISH-based techniques, rearrangements of the immunoglobulin heavy-chain (IgH) locus at 14q32 have been found in the majority of cases of multiple myeloma (MM). Some of these IgH translocations are...
18.
Rawstron A, Davies F, Dasgupta R, Ashcroft A, Patmore R, Drayson M, et al.
Blood
. 2002 Oct;
100(9):3095-100.
PMID: 12384404
Conventional monitoring strategies for myeloma are not sufficiently sensitive to identify patients likely to benefit from further therapy immediately after transplantation. We have used a sensitive flow cytometry assay that...