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A J Visser

Explore the profile of A J Visser including associated specialties, affiliations and a list of published articles. Areas
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Articles 126
Citations 681
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Recent Articles
11.
van den Berg P, Widengren J, Hink M, Rigler R, Visser A
Spectrochim Acta A Mol Biomol Spectrosc . 2001 Oct; 57(11):2135-44. PMID: 11603835
Fluorescence Correlation Spectroscopy (FCS) was used to investigate the excited-state properties of flavins and flavoproteins in solution at the single molecule level. Flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD) and...
12.
Heyns C, Naude A, Ahmed G, Stopforth H, Stellmacher G, Visser A
S Afr Med J . 2001 Oct; 91(8):685-9. PMID: 11584785
Introduction: To determine whether there is a cut-off value of serum prostate-specific antigen (PSA) which can be used confidently to make the diagnosis of prostate cancer, thereby obviating the need...
13.
Heyns C, Naude A, Visser A, Marais D, Stopforth H, Nyarko J, et al.
S Afr Med J . 2001 Oct; 91(8):679-84. PMID: 11584784
Background: Early stage prostate cancer does not cause symptoms, and even metastatic disease may exist for years without causing symptoms or signs. Whereas early stage prostate cancer can be cured...
14.
van den Berg P, Mulrooney S, Gobets B, van Stokkum I, van Hoek A, Williams Jr C, et al.
Protein Sci . 2001 Sep; 10(10):2037-49. PMID: 11567095
The conformational dynamics of wild-type Escherichia coli thioredoxin reductase (TrxR) and the mutant enzyme C138S were studied by ultrafast time-resolved fluorescence of the flavin cofactor in combination with circular dichroism...
15.
Minekus J, Visser A, van Mastrigt R
Urol Int . 2001 Jul; 67(1):62-8. PMID: 11464119
Background: Smooth muscle fibers can be stimulated with an electrical field, high potassium or carbachol. We studied the effect of combined, supramaximal stimulation on the isometric force and the maximum...
16.
Visser A, van Mastrigt R
Urol Int . 2001 Jun; 66(4):205-11. PMID: 11385307
Introduction: The primary key to pharmacotherapy of bladder instability is in the excitation-contraction coupling of detrusor smooth muscle cells. To study this process, simultaneous recordings of mechanical and electrical activity...
17.
van Slooten M, Visser A, van Hoek A, Storm G, Crommelin D, Jiskoot W
J Pharm Sci . 2000 Oct; 89(12):1605-19. PMID: 11042609
The integrity of a therapeutic protein has to be safeguarded when formulated in delivery systems such as liposomes. In this study, we investigated the conformational stability of recombinant human interferon...
18.
Uskova M, Borst J, Hink M, van Hoek A, Schots A, Klyachko N, et al.
Biophys Chem . 2000 Oct; 87(1):73-84. PMID: 11036971
We have used the enhanced green fluorescent protein (EGFP) to investigate the properties of surfactant-entrapped water pools in organic solvents (reversed micelles) with steady-state and time-resolved fluorescence methods. The surfactant...
19.
Visser A, van Mastrigt R
Urology . 2000 Oct; 56(4):696-701. PMID: 11018641
Objectives: To study the relationship between the electrical and mechanical activity of guinea-pig detrusor muscle and compare this with the results obtained in human tissue. The guinea pig is the...
20.
Visser A, van Mastrigt R
Urol Res . 2000 Sep; 28(4):260-8. PMID: 11011966
We studied the role of extracellular and intracellular Ca2+ in human detrusor smooth muscle contraction. Simultaneous recordings of mechanical and intracellular electrical activity were made in three different Ca2+ concentrations:...