A J Obaya
Overview
Explore the profile of A J Obaya including associated specialties, affiliations and a list of published articles.
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8
Citations
812
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0
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Recent Articles
1.
El Hour M, Moncada-Pazos A, Blacher S, Masset A, Cal S, Berndt S, et al.
Oncogene
. 2010 Mar;
29(20):3025-32.
PMID: 20208563
ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin motifs) constitute a family of endopeptidases related to matrix metalloproteinases. These proteases have been largely implicated in tissue remodeling and angiogenesis associated...
2.
Obaya A, Sedivy J
Cell Mol Life Sci
. 2002 Feb;
59(1):126-42.
PMID: 11846025
Cell cycle progression is driven by the coordinated regulation of the activities of cyclin-dependent kinases (Cdks). Of the several mechanisms known to regulate Cdk activity in response to external signals,...
3.
Adachi S, Obaya A, Han Z, Wyche J, Sedivy J
Mol Cell Biol
. 2001 Jul;
21(15):4929-37.
PMID: 11438650
The c-myc proto-oncogene encodes a transcription factor that participates in the regulation of cellular proliferation, differentiation, and apoptosis. Ectopic overexpression of c-Myc has been shown to sensitize cells to apoptosis....
4.
Hermeking H, Rago C, Schuhmacher M, Li Q, Barrett J, Obaya A, et al.
Proc Natl Acad Sci U S A
. 2000 Feb;
97(5):2229-34.
PMID: 10688915
The prototypic oncogene c-MYC encodes a transcription factor that can drive proliferation by promoting cell-cycle reentry. However, the mechanisms through which c-MYC achieves these effects have been unclear. Using serial...
5.
Obaya A, Mateyak M, Sedivy J
Oncogene
. 1999 Jun;
18(19):2934-41.
PMID: 10378690
A large body of physiological evidence shows that either upregulation or downregulation of intracellular c-Myc activity has profound consequences on cell cycle progression. Recent work suggests that c-Myc may stimulate...
6.
Mateyak M, Obaya A, Sedivy J
Mol Cell Biol
. 1999 Jun;
19(7):4672-83.
PMID: 10373516
c-myc is a cellular proto-oncogene associated with a variety of human cancers and is strongly implicated in the control of cellular proliferation, programmed cell death, and differentiation. We have previously...
7.
Mateyak M, Obaya A, Adachi S, Sedivy J
Cell Growth Differ
. 1997 Oct;
8(10):1039-48.
PMID: 9342182
Rat fibroblast cell lines with targeted disruptions of both c-myc gene copies were constructed. Although c-myc null cells are viable, their growth is significantly impaired. The absence of detectable N-myc...
8.
Obaya A, Guijarro J
J Bacteriol
. 1993 May;
175(10):3220-3.
PMID: 8491738
Incubation of [alpha-32P]GTP with cellular extracts or membranes of Streptomyces coelicolor labels a protein of 43 kDa, which was also labeled with [8,5'-3H]GTP but not with [alpha-32P]ATP or [gamma-32P]GTP. Radioactivity...