A J Hapel
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Explore the profile of A J Hapel including associated specialties, affiliations and a list of published articles.
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61
Citations
706
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Recent Articles
11.
Mak N, Fung M, Leung K, Hapel A
Cell Immunol
. 1993 Aug;
150(1):1-14.
PMID: 7688266
We have isolated a subclone (JCS) of the WEHI 3B myelomonocytic leukemia, which acquires the characteristics of mature macrophage lineage cells in the presence of PMA or noncytotoxic concentrations of...
12.
Townsend P, Crouch M, Mak N, Hapel A
Growth Factors
. 1993 Jan;
9(1):21-30.
PMID: 8347349
We have examined the role of Gi alpha in haemopoietic cells using the myelomonocytic progenitor cell lines FDC-P1 and WEHI-3B (JCS). During growth factor-dependent proliferation of FDC-P1 cells Gi alpha...
13.
Hapel A, Fung M, Mak N, Morris C, Metcalf D, Nicola N
Br J Haematol
. 1992 Nov;
82(3):488-93.
PMID: 1486029
Haemopoietic cells from A/J mice do not form colonies (proliferate) in response to interleukin-3 (multi-CSF, IL-3). We have examined different populations of cells from A/J mice and shown that, despite...
14.
Smith J, Telford R, Baker M, Hapel A, Weidemann M
J Appl Physiol (1985)
. 1992 Oct;
73(4):1396-401.
PMID: 1447084
We investigated whether increased concentrations of circulating cytokines may be responsible for exercise-induced priming of blood neutrophils (J. A. Smith et al. Int. J. Sports Med. 11: 179-187, 1990). The...
15.
Fung M, Mak N, Leung K, Hapel A
J Immunol Methods
. 1992 Apr;
149(1):97-103.
PMID: 1583316
A set of primers (MF43, MF44 and MF45) were designed and used in the polymerase chain reaction to distinguish between the expression of mouse IL-3 receptor and mouse IL-3 receptor-like...
16.
Fung M, Mak N, Leung K, Hapel A
Cell Immunol
. 1992 Apr;
141(1):121-30.
PMID: 1555246
Four myeloid cell lines (M1, WEHI-3B D+, FDC-P1, and 32D) were screened for the presence of J11d antigen. One of these cell lines, the myeloid leukemia M1, was found to...
17.
Pullman W, Elsbury S, Kobayashi M, Hapel A, Doe W
Gastroenterology
. 1992 Feb;
102(2):529-37.
PMID: 1370662
Proliferation, maturation, chemotaxis, and activation of neutrophils and monocytes are mediated largely by cytokines, including colony-stimulating factors and lymphokines. Cytokines produced in the intestinal mucosa contribute to the increased migration...
18.
Kobayashi M, Imamura M, Gotohda Y, Maeda S, Iwasaki H, Sakurada K, et al.
Blood
. 1991 Oct;
78(8):1947-53.
PMID: 1717075
In the present study, we show that recombinant human interleukin-1 beta (rhIL-1 beta), which has no effect on the proliferation of human progenitor cells, has synergistic effects on the expansion...
19.
Hogan P, Gibson P, Hapel A, Doe W
J Gastroenterol Hepatol
. 1991 Sep;
6(5):455-60.
PMID: 1932665
The role of non-specific cytotoxicity in the pathogenesis of inflammatory bowel disease (IBD) was investigated by assaying the natural killer (NK) and lymphokine-activated killer (LAK) cell activity of lamina propria...
20.
Kobayashi M, Mullbacher A, Waring P, Hapel A
Eur J Haematol
. 1991 Apr;
46(4):205-11.
PMID: 1707826
Gliotoxin, an epipolythiodioxopiperazine, is a fungal metabolite that causes genomic DNA degradation preferentially in certain blood cell types including T lymphocytes and macrophages. Gliotoxin has previously been used to treat...