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A I F Blakemore

Explore the profile of A I F Blakemore including associated specialties, affiliations and a list of published articles. Areas
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Articles 11
Citations 478
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Recent Articles
1.
Murphy J, Uttamlal T, Schmidtke K, Vlaev I, Taylor D, Ahmad M, et al.
BMC Med Inform Decis Mak . 2020 Feb; 20(1):17. PMID: 32013996
Background: Within the United Kingdom's National Health System (NHS), patients suffering from obesity may be provided with bariatric surgery. After receiving surgery many of these patients require further support to...
2.
Ruffmann C, Calboli F, Bravi I, Gveric D, Curry L, de Smith A, et al.
Neuropathol Appl Neurobiol . 2015 Nov; 42(5):436-50. PMID: 26527105
Aims: Our main objective was to determine the neuropathological correlates of dementia in patients with Lewy body disease (LBD). Furthermore, we used data derived from clinical, neuropathological and genetic studies...
3.
Al-Hassi H, Bernardo D, Murugananthan A, Mann E, English N, Jones A, et al.
Mucosal Immunol . 2012 Nov; 6(4):751-61. PMID: 23168838
Dendritic cells (DC) migrate to lymph nodes on expression of C-C motif chemokine receptor 7 (CCR7) and control immune activity. Leptin, an immunomodulatory adipokine, functions via leptin receptors, signaling via...
4.
Dorajoo R, Blakemore A, Sim X, Ong R, Ng D, Seielstad M, et al.
Int J Obes (Lond) . 2011 May; 36(1):159-63. PMID: 21544081
Objective: Recent genome-wide association studies (GWAS) have identified 38 obesity-associated loci among European populations. However, their contribution to obesity in other ethnicities is largely unknown. Methods: We utilised five GWAS...
5.
Walters R, Jacquemont S, Valsesia A, de Smith A, Martinet D, Andersson J, et al.
Nature . 2010 Feb; 463(7281):671-5. PMID: 20130649
Obesity has become a major worldwide challenge to public health, owing to an interaction between the Western 'obesogenic' environment and a strong genetic contribution. Recent extensive genome-wide association studies (GWASs)...
6.
Salah Khalil M, El Nahas A, Blakemore A
Nephron Exp Nephrol . 2005 Jun; 101(2):e31-41. PMID: 15942255
Associations have been described between polymorphisms of cytokine and growth factor genes and susceptibility to, or progression of, an increasing number of diseases. TGF-beta1 plays an important role in the...
7.
Linjawi S, Li T, Tuckerman E, Blakemore A, Laird S
J Reprod Immunol . 2004 Dec; 64(1-2):145-55. PMID: 15596233
Interleukin-11 (IL-11) is a member of the IL-6 family of cytokines. Previous studies have suggested that IL-11 may play a role in human endometrial function. In this study, we have...
8.
Quinton N, Meechan D, Brown K, Eastwood H, Blakemore A
Psychiatr Genet . 2004 Nov; 14(4):191-4. PMID: 15564891
Anorexia nervosa is an eating disorder of unknown aetiology. There is significant evidence for a genetic component in the pathogenesis of this disorder. A region on chromosome 1 has been...
9.
Capper E, Maskill J, Gordon C, Blakemore A
Clin Exp Immunol . 2004 Oct; 138(2):348-56. PMID: 15498048
Several cytokines have been implicated individually in the pathogenesis of systemic lupus erythematosus (SLE) and some, including interleukin (IL)-10, IL-12 and IL-1ra are raised during flares of disease activity. Few...
10.
Quinton N, Laird S, Tuckerman E, Cork B, Li T, Blakemore A
Am J Reprod Immunol . 2003 Nov; 50(3):224-31. PMID: 14629027
Problem: Leptin has a key role to play in human female reproduction. Its receptor is expressed highly throughout the reproductive tract. Cytokines have an important role in preparing the endometrium...