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A Hamsten

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Articles 244
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Recent Articles
11.
Malarstig A, Silveira A, Wagsater D, Ohrvik J, Backlund A, Samnegard A, et al.
J Intern Med . 2011 Feb; 270(3):229-36. PMID: 21332844
Objectives: A common nonsynonymous single nucleotide polymorphism (SNP) in the CD93 gene (rs3746731, Pro541Ser) has been associated with risk of coronary artery disease (CAD). CD93 is a transmembrane glycoprotein, which...
12.
Mellbin L, Hamsten A, Malmberg K, Steffensen R, Ryden L, Ohrvik J, et al.
Diabetes Care . 2010 Aug; 33(11):2451-6. PMID: 20693349
Objective: The present study characterizes mannose-binding lectin (MBL), an activator of the complement system and thereby important for inflammatory activation, in patients with diabetes and myocardial infarction. Research Design And...
13.
Kotronen A, Johansson L, Johansson L, Roos C, Westerbacka J, Hamsten A, et al.
Diabetologia . 2009 Feb; 52(6):1056-60. PMID: 19224197
Aims/hypothesis: It has recently been suggested that the rs738409 G allele in PNPLA3, which encodes adiponutrin, is strongly associated with increased liver fat content in three different ethnic groups. The...
14.
Bjorck H, Lanne T, Alehagen U, Persson K, Rundkvist L, Hamsten A, et al.
J Intern Med . 2008 Nov; 265(3):373-81. PMID: 19019192
Objectives: Genome wide association studies have consistently reported associations between a region on chromosome 9p21.3 and a broad range of vascular diseases, such as coronary artery disease (CAD), aortic and...
15.
Olofsson P, Soderstrom L, Jern C, Sirsjo A, Ria M, Sundler E, et al.
J Mol Med (Berl) . 2008 Nov; 87(4):337-46. PMID: 18998106
In two independent human cohorts, the minor allele of SNP rs3850641 in TNFSF4 was significantly more frequent in individuals with myocardial infarction than in controls. In mice, Tnfsf4 expression is...
16.
Hamsten A, Eriksson P
J Intern Med . 2008 Apr; 263(5):538-52. PMID: 18410597
The genetic basis of coronary artery disease (CAD) is complex, and the fact that an alarmingly high proportion of reported associations between genetic variants and CAD are not replicated has...
17.
Sjogren P, Sierra-Johnson J, Gertow K, Rosell M, Vessby B, de Faire U, et al.
Diabetologia . 2007 Nov; 51(2):328-35. PMID: 18030445
Aims/hypothesis: Fatty acid desaturases introduce double bonds into growing fatty acid chains. The key desaturases in humans are Delta5-desaturase (D5D), Delta6-desaturase (D6D) and stearoyl-CoA desaturase (SCD). Animal and human data...
18.
Elfstrom P, Hamsten A, Montgomery S, Ekbom A, Ludvigsson J
J Intern Med . 2007 Oct; 262(5):545-54. PMID: 17949363
Objectives: We investigated the risk of myocarditis, cardiomyopathy, and pericarditis in patients with celiac disease (CD) from a general population cohort. Subjects And Methods: Through the Swedish national registers we...
19.
Boquist S, Ruotolo G, Skoglund-Andersson C, Tang R, Bjorkegren J, Bond M, et al.
Clin Endocrinol (Oxf) . 2007 Sep; 68(1):51-8. PMID: 17803702
Objectives: IGF-I, IGFBP-1 and IGFBP-3 are putative mediators in cardiovascular disease. The present study examined (i) the correlations of circulating IGF-I, IGFBP-1 and IGFBP-3 to established cardiovascular risk factors and...
20.
Malarstig A, Eriksson P, Hamsten A, Lindahl B, Wallentin L, Siegbahn A
Heart . 2007 Aug; 94(6):724-9. PMID: 17690160
Objectives: To re-evaluate the relation between plasma interleukin-10 (IL-10) concentration at hospital admission and outcome and to investigate the impact of single nucleotide polymorphisms (SNP) in the IL-10 gene in...