A G Kanthasamy
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Explore the profile of A G Kanthasamy including associated specialties, affiliations and a list of published articles.
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30
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531
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Recent Articles
1.
Kanthasamy A, Choi C, Jin H, Harischandra D, Anantharam V, Kanthasamy A
Toxicol Lett
. 2012 Sep;
214(3):288-95.
PMID: 22995398
The role of normal cellular prion protein (PrP) remains to be fully elucidated; however, the protein is crucial for the infection and progression of prion diseases. Recent evidence indicates that...
2.
Lin M, Chandramani-Shivalingappa P, Jin H, Ghosh A, Anantharam V, Ali S, et al.
Neuroscience
. 2012 Mar;
210:308-32.
PMID: 22445524
A compromised protein degradation machinery has been implicated in methamphetamine (MA)-induced neurodegeneration. However, the signaling mechanisms that induce autophagy and ubiquitin-proteasome system (UPS) dysfunction are not well understood. The present...
3.
Wong D, Ghosh A, Fales-Williams A, Haynes J, Kanthasamy A
Vet Pathol
. 2012 Mar;
49(6):1049-53.
PMID: 22390882
The cervical spinal cords of 2 horses with equine degenerative myeloencephalopathy (EDM) were evaluated for evidence of oxidative damage to the central nervous system (CNS) using immunohistochemical staining for 3-nitrotyrosine...
4.
Song C, Kanthasamy A, Jin H, Anantharam V, Kanthasamy A
Neurotoxicology
. 2011 Jul;
32(5):586-95.
PMID: 21777615
Environmental neurotoxic exposure to agrochemicals has been implicated in the etiopathogenesis of Parkinson's disease (PD). The widely used herbicide paraquat is among the few environmental chemicals potentially linked with PD....
5.
Song C, Kanthasamy A, Anantharam V, Sun F, Kanthasamy A
Mol Pharmacol
. 2010 Jan;
77(4):621-32.
PMID: 20097775
Pesticide exposure has been implicated in the etiopathogenesis of Parkinson's disease (PD); in particular, the organochlorine insecticide dieldrin is believed to be associated with PD. Emerging evidence indicates that histone...
6.
Kanthasamy A, Anantharam V, Ali S, Kanthasamy A
Ann N Y Acad Sci
. 2006 Nov;
1074:234-44.
PMID: 17105920
Autophagy is a phylogenetically conserved process that plays a critical role in the degradation of oxidatively damaged proteins and organelle turnover. The role of oxidative stress and apoptosis in methamphetamine...
7.
Anantharam V, Kitazawa M, Latchoumycandane C, Kanthasamy A, Kanthasamy A
Ann N Y Acad Sci
. 2005 Feb;
1035:271-89.
PMID: 15681813
The use of methylcyclopentadienyl manganese tricarbonyl (MMT) as a gasoline additive has raised health concerns and increased interest in understanding the neurotoxic effects of manganese. Chronic exposure to inorganic manganese...
8.
Kanthasamy A, Kitazawa M, Kaul S, Yang Y, Lahiri D, Anantharam V, et al.
Ann N Y Acad Sci
. 2004 Mar;
1010:683-6.
PMID: 15033812
We previously demonstrated that the organochlorine pesticide dieldrin, a potential chemical risk factor for development of Parkinson's disease (PD), impairs mitochondrial function and promotes apoptosis in dopaminergic PC12 cells. We...
9.
Kitazawa M, Anantharam V, Kanthasamy A
Neuroscience
. 2003 Jul;
119(4):945-64.
PMID: 12831855
We previously reported that dieldrin, one of the potential environmental risk factors for development of Parkinson's disease, induces apoptosis in dopaminergic cells by generating oxidative stress. Here, we demonstrate that...
10.
Kitazawa M, Anantharam V, Kanthasamy A
Free Radic Biol Med
. 2001 Dec;
31(11):1473-85.
PMID: 11728820
We examined the acute toxicity of dieldrin, a possible environmental risk factor of Parkinson's disease, in a dopaminergic cell model, PC12 cells, to determine early cellular events underlying the pesticide-induced...