A Dharmarajan
Overview
Explore the profile of A Dharmarajan including associated specialties, affiliations and a list of published articles.
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Snapshot
Articles
13
Citations
296
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0
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Recent Articles
1.
Deshmukh A, Kumar S, Arfuso F, Newsholme P, Dharmarajan A
Sci Rep
. 2017 May;
7(1):2256.
PMID: 28536422
This study investigated molecular signals essential to sustain cancer stem cells (CSCs) and assessed their activity in the presence of secreted frizzled-related protein 4 (sFRP4) alone or in combination with...
2.
Pohl S, Brook N, Agostino M, Arfuso F, Kumar A, Dharmarajan A
Oncogenesis
. 2017 Apr;
6(4):e310.
PMID: 28368389
Wnt signaling regulates a variety of cellular processes, including cell fate, differentiation, proliferation and stem cell pluripotency. Aberrant Wnt signaling is a hallmark of many cancers. An aggressive subtype of...
3.
Warrier S, Bhuvanalakshmi G, Arfuso F, Rajan G, Millward M, Dharmarajan A
Cancer Gene Ther
. 2014 Aug;
21(9):381-8.
PMID: 25104726
Cancer stem cells (CSCs) of head and neck squamous cell carcinoma (HNSCC) are defined by high self-renewal and drug refractory potential. Involvement of Wnt/β-catenin signaling has been implicated in rapidly...
4.
Schiefer L, Visweswaran M, Perumal V, Arfuso F, Groth D, Newsholme P, et al.
Cancer Gene Ther
. 2014 Jun;
21(7):297-303.
PMID: 24948145
Glioblastoma multiforme (GBM) are intracranial tumors of the central nervous system and the most lethal among solid tumors. Current therapy is palliative and is limited to surgical resection followed by...
5.
Warrier S, Haridas N, Balasubramanian S, Jalisatgi A, Bhonde R, Dharmarajan A
Cell Prolif
. 2013 May;
46(3):283-90.
PMID: 23692087
Objectives: Mesenchymal stem cells (MSCs) derived from post-natal tissues offer a suitable source of MSCs for cellular therapy. Limitation of the use of MSCs for therapeutic purposes is attributed to...
6.
Drake J, Shearwood A, White J, Friis R, Zeps N, Charles A, et al.
Eur J Gynaecol Oncol
. 2009 Jun;
30(2):133-41.
PMID: 19480240
Objective: Serous ovarian cancer is the most prevalent type of ovarian cancer. The majority of women present at an advanced stage and patient survival is poor. Resistance to chemotherapy is...
7.
White L, Suganthini G, Friis R, Dharmarajan A, Charles A
Reprod Biomed Online
. 2009 Jan;
18(1):104-10.
PMID: 19146776
Secreted frizzled-related protein 4 (sFRP4) blocks the Wnt signalling pathway by competitively binding Wnt ligands (frizzled receptors). This pathway is important during development and oncogenesis. It is, however, complex with...
8.
White L, Dharmarajan A, Charles A
Reprod Biomed Online
. 2007 Mar;
14(3):300-7.
PMID: 17359582
The human placenta is responsible for the exchange of nutrients, gas and wastes through the trophoblast maternal-fetal barrier, which is formed by the fusion of villous cytotrophoblasts to form the...
9.
Vijayababu M, Kanagaraj P, Arunkumar A, Ilangovan R, Dharmarajan A, Arunakaran J
Oncol Res
. 2006 Aug;
16(2):67-74.
PMID: 16898267
Quercetin, a flavonoid found in onion, grapes, green vegetables, etc., has been shown to possess potent antiproliferative effects against various malignant cells. We report insulin-like growth factor-binding protein-3 (IGFBP-3) as...
10.
Worawittayawong P, Leigh C, Cozens G, Peirce E, Setchell B, Sretarugsa P, et al.
Int J Androl
. 2005 May;
28(3):180-8.
PMID: 15910544
In the greater bandicoot rat, Bandicota indica, of south-east Asia, nine cell associations were documented in the testicular seminiferous epithelium. In about 10% of the tubule cross sections two or...