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A David Burden

Explore the profile of A David Burden including associated specialties, affiliations and a list of published articles. Areas
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Articles 66
Citations 2968
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Recent Articles
1.
Farag A, Visvanathan S, Bachelez H, Morita A, Lebwohl M, Barker J, et al.
J Invest Dermatol . 2024 Jul; 145(3):573-582.e8. PMID: 39004117
EFFISAYIL 1 was a randomized, placebo-controlled study of spesolimab, an anti-IL-36 receptor antibody, in patients presenting with a generalized pustular psoriasis flare. Treatment with spesolimab led to more rapid pustular...
2.
Hernandez-Cordero A, Thomas L, Smail A, Lim Z, Saklatvala J, Chung R, et al.
J Allergy Clin Immunol . 2024 May; 154(3):657-665.e9. PMID: 38815935
Background: Palmoplantar pustulosis (PPP) is an inflammatory skin disorder that mostly affects smokers and manifests with painful pustular eruptions on the palms and soles. Although the disease can present with...
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Burden A, Bissonnette R, Anatchkova M, Budhiarso I, Skalicky A, Liberato A, et al.
J Eur Acad Dermatol Venereol . 2024 Feb; 38(7):1383-1390. PMID: 38334243
Background: Generalized pustular psoriasis (GPP) is a rare, chronic, inflammatory skin disease associated with considerable patient burden. The Psoriasis Symptom Scale (PSS), Functional Assessment of Chronic Illness Therapy-Fatigue (FACIT-Fatigue) and...
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Smith C, Yiu Z, Bale T, Burden A, Coates L, Eckert E, et al.
Br J Dermatol . 2023 Sep; 190(2):270-272. PMID: 37740557
No abstract available.
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Morita A, Strober B, Burden A, Choon S, Anadkat M, Marrakchi S, et al.
Lancet . 2023 Sep; 402(10412):1541-1551. PMID: 37738999
Background: Spesolimab is an anti-interleukin-36 receptor monoclonal antibody approved to treat generalised pustular psoriasis (GPP) flares. We aimed to assess the efficacy and safety of spesolimab for GPP flare prevention....
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Burden A, Bissonnette R, Navarini A, Murakami M, Morita A, Haeufel T, et al.
Dermatol Ther (Heidelb) . 2023 Sep; 13(10):2279-2297. PMID: 37731086
Introduction: We evaluated the anti-interleukin-36 receptor antibody spesolimab in patients with moderate-to-severe palmoplantar pustulosis (PPP). Methods: This phase IIb trial comprised a loading dose period to week (W) 4, then...
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Burden A, Bachelez H, Choon S, Marrakchi S, Tsai T, Turki H, et al.
Br J Dermatol . 2023 Apr; 189(1):138-140. PMID: 37075220
No abstract available.
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Burden A
Expert Rev Clin Immunol . 2023 Mar; 19(5):473-481. PMID: 36960829
Introduction: Generalized pustular psoriasis (GPP) is a rare cutaneous and systemic inflammatory disease which is characterized by flares of widespread painful pustulation of the skin, often associated with fever and...
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Burden A, Bissonnette R, Lebwohl M, Gloede T, Anatchkova M, Budhiarso I, et al.
J Eur Acad Dermatol Venereol . 2023 Mar; 37(7):1327-1335. PMID: 36854864
Background: Generalized pustular psoriasis (GPP) is a rare and life-threatening skin disease often accompanied by systemic inflammation. There are currently no standardized or validated GPP-specific measures for assessing severity. Objective:...